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Development of an Epileptic Seizure Detection Algorithm by Continuous Analysis of the Electrocardiogram

Development of an Epileptic Seizure Detection Algorithm by Continuous Analysis of the Electrocardiogram

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03369522
Acronym
EPICARD
Enrollment
40
Registered
2017-12-12
Start date
2017-12-13
Completion date
2019-12-12
Last updated
2025-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electrocardiography, Epilepsy, Seizures

Keywords

seizure detection

Brief summary

The aim of our project is to develop an epileptic seizure detection algorithm based on the the continuous analysis of the Electrocardiogram

Detailed description

In a first step, the team will build a multi-parametric algorithm on existing records issued from the Epilepsy Monitoring Units. Each selected record will be analyzed by EMU medical team in order to detect seizure on the EEG. The algorithm will adapt in order to obtain the best sensitivity and specificity regarding seizure detection. in a second step,algorithm will validate on a cohort of other recordings in patients with epilepsy

Interventions

None listed

Sponsors

University Hospital, Lille
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients with epilepsy * with a long-term video-EEG recording * 1 (or more) seizure (s) recorded * onset seizure clearly defined on the basis of the EEG

Exclusion criteria

* bad quality of the Electrocardiogram recording * pace-maker * non sinus rhythm

Design outcomes

Primary

MeasureTime frameDescription
ROC curve for seizure detection24 monthsROC curve gives the relation between detection probability and false alarm probability of the algorithm that will be developped

Secondary

MeasureTime frameDescription
Time of detection of seizures24 monthsTime of detection of seizures by the algorithm
ROC curve for Psychogenic seizure detection24 monthsROC curve for Psychogenic seizure detection

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026