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Caudal Blockade and Electrocardiographic Changes

Caudal Blockade and Electrocardiographic Changes

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03368833
Enrollment
5
Registered
2017-12-11
Start date
2017-12-15
Completion date
2022-09-06
Last updated
2023-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Regional Anesthesia Morbidity

Brief summary

Caudal epidural blockade is frequently used as an adjunct to general anesthesia in children for perioperative analgesia. Intravascular injection of local anesthetic is a known complication that can adversely affect the neurological and cardiovascular systems. This study will look at the delayed effects of a caudal epidural block on the electrical activity of the patient's myocardium by trying to characterize the incidence of ECG changes within 60 minutes after the caudal dose is given.

Interventions

DIAGNOSTIC_TESTElectrocardiogram

12-lead ECG will be obtained after induction and at 5, 10, 20, 30, and 60 minutes after the caudal epidural block.

Sponsors

Senthil G. Krishna
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No

Inclusion criteria

* ASA grade 1 or 2 * Receiving general anesthesia with a caudal block

Exclusion criteria

* Preexisting cardiac comorbidities

Design outcomes

Primary

MeasureTime frameDescription
Change in T wave amplitudeBaseline to 60 mins. post caudalChange in T wave amplitude on the ECG tracings
Change in T wave widthBaseline to 60 mins. post caudalChange in T wave width on the ECG tracings

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026