Comparative Study of Medial-to-Lateral Approach vs Dorsal and Medial Hybrid Approach in Laparoscopic Right Hemicolectomy

Randomized Controlled Trial: Comparative Study of Medial-to-Lateral Approach vs Dorsal and Medial Hybrid Approach in Laparoscopic Right Hemicolectomy

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03364478

Enrollment

326

Registered

2017-12-06

Start date

2018-01-01

Completion date

2022-01-01

Last updated

2017-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overall Survival, Postoperative Complications

Keywords

Surgical approach, Laparoscopic right hemicolectomy

Brief summary

To standardize the surgery for advanced right hemi colon cancer with laparoscopy and investigate whether dorsal and medial hybrid approach could improve disease-free survival in patients with right colon cancer, compared with traditional medial-to-lateral approach in laparoscopic righ hemicolectomy.

Interventions

PROCEDUREDML group

The group underwent laparoscopic right hemicolectomy with dorsal and medial hybrid approach.

PROCEDUREMLA group

The group underwent laparoscopic right hemicolectomy with traditional medial-to-lateral approach.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Aged more then 18 years old; * Diagnosed as right hemi colonic cancer with colonoscopic biopsy; * Without metastasis; * No Invasion of surrounding tissues; * Limited operation; * Underwent laparoscopic radical right hemicolectomy (L-right hemicolectomy); * BMI 18\ 30kg/m2; * Without multiple primary tumors; * Sign on the Medical informed Consent.

Exclusion criteria

* Simultaneous or simultaneous multiple primary colorectal cancer; * Preoperative imaging examination results show: 1. Tumor involves the surrounding organs and combined organ resection need to be done; 2. Distant metastasis; 3. Unable to perform R0 resection; * History of any other malignant tumor in recent 5 years; * Patients need emergency operation; * Not suitable for laparoscopic surgery; * Women during Pregnancy or breast feeding period; * Informed consent refusal

Design outcomes

Primary

Measure	Time frame
Disease-free survival	3 years

Secondary

Measure	Time frame
The rate of postoperative complication	30 days
3 years overall survival	3 years
The rate of local and distant recurrence	3 years

Countries

China

Contacts

Primary ContactMinhua Zheng, PhD

zmhtiger@yeah.net+86-13564119545

Backup ContactHiju Hong, PhD Student

jing12722@naver.com+86-13564119545

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026