Squamous Cell Carcinoma of the Oral Cavity
Conditions
Keywords
buccal squamous cell carcinoma
Brief summary
Evaluation of local control in buccinator muscle excision with the skin versus buccinator muscle excision without the skin in buccal squamous cell carcinoma: A randomized clinical trial.
Detailed description
Preoperative Multi Slice CT scan or MRI carried out for evaluation the lymph node of the neck. Also, ultrasound carried out for measuring the depth of invasion of the tumour in the cheek (The invasion in the buccinator muscle). * Under general anaesthesia, the buccal squamous cell carcinoma which invaded the buccinator muscle will be excised with the skin of the cheek. This will be done by a safety margins in the soft tissue and the mandible may be resected according to the plan and the invasion of the tumour. * A neck dissection will be done in all cases of negative or positive neck lymph node. * Reconstruction of the soft tissue will be done immediately by a major pectorals flap with the skin, also bony reconstruction may be done by a reconstructed plate at the time of surgery then the patients will be prepared for bone graft in another surgery.
Interventions
PROCEDUREsurgical excision
* Under general anaesthesia, the buccal squamous cell carcinoma which invaded the buccinator muscle will be excised with the skin of the cheek. This will be done by a safety margins in the soft tissue and the mandible may be resected according to the plan and the invasion of the tumour. * A neck dissection will be done in all cases of negative or positive neck lymph node. * Reconstruction of the soft tissue will be done immediately by a major pectorals flap with the skin, also bony reconstruction may be done by a reconstructed plate at the time of surgery then the patients will be prepared for bone graft in another surgery.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients suffering from buccal squamous cell carcinoma. * Patients should be free from any systemic disease that may affect normal healing, and predictable outcome. * Both sexes and all ages will be included in the study. * Cooperative patients, who accept the procedure and return for follow up , examination and evaluation.
Exclusion criteria
* Patients with any systemic disease that may affect normal healing.9,10 * Patients who physically and psychologically not able to tolerate the procedures. * Patients may discontinue the follow up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| local control | up to 1 year | (recurrence rate) |
Contacts
Primary Contactahmed yousef, PHD
Outcome results
None listed