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Prenatal Diagnosis of Antenatal Midgut Volvulus: Specific Ultrasound Features

Prenatal Diagnosis of Antenatal Midgut Volvulus: Specific Ultrasound Features

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03362450
Enrollment
13
Registered
2017-12-05
Start date
2006-01-01
Completion date
2017-09-30
Last updated
2017-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal Volvulus, Midgut Volvulus

Keywords

Midgut volvulus, Fetal volvulus, Whirlpool sign, Pregnant women, Position of mesenteric vessels, Post natal surgery, Foetopathology if performed, Hydro-meconium level in the dilated loops

Brief summary

Objective: The small bowel volvulus is a rare cause of intestinal obstruction which may occur in utero and whose prenatal diagnosis is difficult.Sonographic signs are mainly indirect and non specific.The aim of this study is to present a retrospective analysis of prenatal sonographicfindings in fetal segmental midgut volvulus.Thanks to this series the investigators could highlight the more specifics signs of the volvulus included a new pattern.

Detailed description

Objective: The small bowel volvulus is a rare cause of intestinal obstruction which may occur in utero and whose prenatal diagnosis is difficult. Sonographic signs are mainly indirect and nonspecific. The aim of this study is to present a retrospective analysis of prenatal sonographic findings in fetal segmental midgut volvulus. Thanks to this series the investigators could highlight the more specifics signs of the volvulus included a new pattern. Methods: Unicentric retrospective analysis of cases of prenatal midgut volvulus between 2006 and 2017. The primary inclusion criteria was postnatal diagnosis of prenatal volvulus based on post-natal findings and prenatal imaging findings. The exclusion criteria was the absence of prenatal imaging assessment. The investigators collected the clinical history and the echographic mode B and color Doppler. They have searched for some specific sign like whirlpool sign representing the winding of the mesenteric vein around the superior mesenteric arterywith color Doppler with arciform pattern of the midgut, hydro-meconium level in the dilated loops and position of mesenteric vessels for evaluation of the intestinal (mal) rotation. Gold standard was surgery or foetopathology if performed.

Interventions

OTHERFetal ultrasound during the second or third trimester/ Postnatal surgery / Post mortem examination

Fetal ultrasound during the second or third trimester Postnatal surgery Post mortem examination

Sponsors

University Hospital, Montpellier
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* postnatal diagnosis of prenatal volvulus based on post-natal findings and prenatal imaging findings

Exclusion criteria

* the absence of prenatal imaging assessment

Design outcomes

Primary

MeasureTime frameDescription
echographyduring the second (22-24 weeks) after ultrasound screeningObservation of specific signs using echography for the diagnosis of fetal during the second (22-24 weeks) and the third (31-34 weeks) trimester after ultrasound screening and when diagnostic ultrasound were performedmidgut volvulus

Secondary

MeasureTime frameDescription
ultrasound signs of complicationthe third (31-34 weeks) after ultrasound screeningObservation of ultrasound signs of complication of midgut volvulus during the pregnancy like meconial pseudocyst, ascites, meconial peritonitis.
presence or not of the volvulus1 dayObservation of surgery outcome like presence or not of the volvulus after diagnostic ultrasound
presence or not ileal atresia.during the second (22-24 weeks) after ultrasound screeningObservation of surgery outcome like presence or not ileal atresia

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026