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Blood Pressure in Adolescents With PReclampsia and Eclampsia.

Levels of Blood Pressure in Adolescents With Preclampsia and Eclampsia: Study of Cases and Controls.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03360240
Acronym
ADPRE
Enrollment
1050
Registered
2017-12-04
Start date
2017-08-01
Completion date
2018-03-08
Last updated
2018-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent Pregnancy, Preeclampsia and Eclampsia

Brief summary

Levels of blood pressure in adolescents with preeclampsia and eclampsia: Multicenter case-control study (Latin America). Maternities in Latin America: Two hospitals in Panama, one hospital in Mexico, one hospital in El Salvador, one hospital in Guatemala, two hospitals in Honduras, one hospital in Colombia, two hospitals in Peru and two hospitals in Bolivia. The objective is to evaluate the basal levels of blood pressure during pregnancy and determine if there is any increase that is associated with the development of preeclampsia and eclampsia without reaching the known values of 140/90 mm Hg. The sample is 1050: (350 Cases and 700 Controls).

Detailed description

Levels of blood pressure in adolescents with preeclampsia and eclampsia: cases and controls study. It is unknown whether the blood pressure levels used for the diagnosis of preeclampsia have the same impact in adolescents as in older women, however for the diagnosis of preeclampsia and severe hypertension the same criteria of hypertension are used regardless of age maternal. It is necessary to do research to determine the values of blood pressure with which adolescents convulse and also to validate if slight increases in baseline blood pressure in adolescents are associated with prediction of preeclampsia and eclampsia. Unfortunately, 85% of teenage pregnancies occur in non-industrialized countries such as those in Latin America, and it is estimated that 25% of maternal deaths occur in adolescents Cases: patients with pregnancy that starts before the age of 19 that develops preeclampsia (mild), severe preeclampsia, gestational hypertension and eclampsia, that is 24 and more weeks pregnant with prenatal control started before 20 weeks of pregnancy. Controls are patients with the same criteria but WITHOUT hypertension during this pregnancy. The statistical analyzes are based on comparing blood pressure levels between the two groups, in addition blood pressure levels like 30/15 on the systolic and diastolic basal levels will be created and compared between the two groups, especially when it is not possible to have 140 / 90 mm Hg.

Interventions

None listed

Sponsors

Complejo Hospitalario Dr. Arnulfo Arias Madrid
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
12 Years to 19 Years
Healthy volunteers
No

Inclusion criteria

* Criteria for inclusion cases: Patients with pregnancy that starts before the age of 19 that develops preeclampsia (mild), severe preeclampsia, gestational hypertension and eclampsia, that has 24 and more weeks of pregnancy with prenatal control started before 20 weeks of age. pregnancy. That you get the data of the termination of your pregnancy.

Exclusion criteria

* Patients with pregnancy that starts before 19 years of age that does NOT develop preeclampsia (mild), severe preeclampsia, gestational hypertension and eclampsia, that has 24 and more weeks of pregnancy with prenatal control started before 20 weeks of pregnancy. That you get the data of the termination of your pregnancy.

Design outcomes

Primary

MeasureTime frameDescription
Levels of blood pressureafter 24 weeks of gestactión to delivery.Level of blood pressure during pregnancy or delivery

Secondary

MeasureTime frameDescription
paritybirth before actual pregancynumber of previous birth
severe hypertensionafter 24 weeks of gestactión to delivery.hypertension more thet 160 mmHg on systolic or 110 mmHg on diastolyc.

Countries

Bolivia, Colombia, Guatemala, Honduras, Panama, Peru

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026