Blood Pressure Measurement Methods and Prediction of Intracranial Hemorrhage After Thrombectomy in Stroke

Impact of Blood Pressure Measurement Methods for the Prediction of Intracranial Hemorrhage After Thrombectomy in Acute Stroke

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03359434

Acronym

BP-METROLOGY

Enrollment

455

Registered

2017-12-02

Start date

2018-12-05

Completion date

2024-12-04

Last updated

2026-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Stroke, Blood Pressure, Cerebral Hemorrhage

Keywords

Acute Stroke, Blood Pressure, Cerebral Hemorrhage

Brief summary

A monocentric, non-randomized, prospective study in which each patient is his/her own control. The study investigates 2 methods of blood pressure measurement, within the first 24 hours after reperfusion, i) Continuous measurement of blood pressure with the Clearsight device (Edwards) and ii) intermittent blood pressure measurements with cuff.

Detailed description

Patients will be followed for 72 hours: * inclusion after reperfusion: clinical evaluation with NIHSS (National Institute of Health Stroke Score) score, measurement of blood pressure. * within 24 hours after reperfusion: blood pressure measurements * at 24 hours: NIHSS score. * Between 24 and 36 hours :cerebral scan (assessment of hemorrhagic transformations and cerebral infarction volumes). * 72 hours after reperfusion: brain scanner in case of hyperdensity on the initial scanner

Interventions

DEVICEClearsight device (Edwards) around the finger

Continuous measurement of blood pressure with the Clearsight device (Edwards) around the finger, within 24 hours after reperfusion:

DEVICEIntermittent blood pressure measurements with cuff.

Standard method: 35 blood pressure measurements with cuff within 24 hours after reperfusion

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient aged 18 years or older * Treated for occlusion of the internal carotid arteries and/or proximal middle cerebral arteries (M1 and M2 segments), vertebral artery, and/or basilar artery * Affiliated with or beneficiary of a Social Security plan * Having received informed information about the study and having given consent to participate in the study

Exclusion criteria

* Per-procedure hemorrhagic complications (before reperfusion is achieved) * Patient benefiting from legal protection measures * Pregnant or breastfeeding women

Design outcomes

Primary

Measure	Time frame	Description
Occurence of intracranial hemorrhagic complications	36 hours after baseline	number of intracranial hemorrhagic complications (symptomatic or asymptomatic) on brain scanner, evaluated with a double centralized blind reading

Countries

France

Contacts

PRINCIPAL_INVESTIGATORMAZIGHI Mikael, MD PhD

Fondation Ophtalmologique A. de Rothschild

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 10, 2026