Osteoporosis
Conditions
Keywords
Osteoporosis, Bone Diseases
Brief summary
To test the changes in osteoarthritis according to the X-rays, and changes in bone quality before and 1 or more years after beginning the jogging
Detailed description
Patients in this research are given an entry Bone Densitometry(DEXA)scan and are required to advance from 3-minute jogging a day to 10-minute level in daily practice for 1 year as instructed. After 1 year, subsequent DEXA scans are recorded. Interested participants are also encouraged to have hip and spine X-rays, and bone quality studies on study entry and two years later. Actual subject participation, intercurrent illnesses, fractures and changes in medication are self-monitored. Results are calculated by change in bone mineral density in the lumbar spine, hips and femurs by the DEXA scan in the study. Dose-response relationships between the amount of jogging and bone mineral density are sought. Jogging-related fractures and other adverse effects are also noted.
Interventions
Jogging as instructed for 1 year
Sponsors
Study design
Eligibility
Inclusion criteria
Past DEXA scan and, all within 6 months of study entry, DEXA scan and normal values for: Metabolic panel, TSH, PTH, ESR (or CRP), Vitamin D 25 hydroxy, Vitamin D 1,25 dihydroxy, Urine NTX
Exclusion criteria
Known metabolic bone disease such as osteogenesis imperfecta, current treatment with steroids, chemotherapy, or currently healing fractures of lumbar spine, hips or femurs, severe heart disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| DEXA T-score | 1 year | Bone mineral density change in spine, hip and femur after 1 year of jogging |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of fractures | 1 year | Number of fractures occurring while in study |