Temperature and Analgesia Monitoring During Cardial Parmonary Bypass

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03358680

Enrollment

Registered

2017-11-30

Start date

2017-05-01

Completion date

2017-09-19

Last updated

2018-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Brief summary

1. Investigator will apply IOC2 to reflect the depth of analgesic during hypothermia in CPB period. 2. effectiveness of IOC2 monitoring for anesthetic depth versus commonly used vital sign monitoring based on factors such as blood pressure and heart rate. 3. Evaluate the other sedation co-relation measurement, include BIS , IOC2 to reflected the consciousness during the operation. 4. Evaluate the other hemodynamic index, include CO, SVV, CVP, PPV to reflect the circulation function , and the effect to the IOC2 and IOC1. 5. Describe the trend of all the measurement. detect the variation of the index during the temperature change during the CPB.

Detailed description

In this study, 1. Investigator will apply IOC2 to reflect the depth of analgesic during hypothermia in CPB period. 2. Furthermore, investigator evaluated the effectiveness of IOC2 monitoring for anesthetic depth versus commonly used vital sign monitoring based on factors such as blood pressure and heart rate. 3. Evaluate the other sedation co-relation measurement, include BIS , IOC2 to reflected the consciousness during the operation. 4. Evaluate the other hemodynamic index, include CO, SVV, CVP, PPV to reflect the circulation function , and the effect to the IOC2 and IOC1. 5. Describe the trend of all the measurement. detect the variation of the index during the temperature change during the CPB.

Interventions

DEVICEnoninvasive analgesia measurement

noninvasive analgesia measurement using index of consciousness(IOC2)

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* undergoing coronary artery bypass surgery

Exclusion criteria

* change the surgery planning during the operation

Design outcomes

Primary

Measure	Time frame	Description
IOC2	1 DAY	Index of consciousness 2

Secondary

Measure	Time frame	Description
BIS	1 DAY	to monitor and compare appropriate conscious value
IOC1	1 DAY	index of consciousness 1

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026