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Night Myopia and Dark Focus of Accommodation

Influence of an Imaginary Target on the State of Accommodation Under Scotopic Conditions

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03358550
Enrollment
39
Registered
2017-11-30
Start date
2017-02-02
Completion date
2017-03-23
Last updated
2017-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dark Focus of Accommodation

Keywords

accommodation, dark focus, night myopia

Brief summary

Shifts in accommodation at decreasing luminance levels are considered as principle cause for night myopia. Previous studies with laser optometers quantified the dark focus of accommodation up to 3 D. In addition to the measurement of dark focus, the aim of this study was to investigate the influence of an imaginary target at finite distances on the state of accommodation at scotopic luminance.

Detailed description

Accommodation was measured by using an open-field autorefractor (WAM 5500, GRAND SEIKO). Full corrected right eyes of 39 subjects aged from 18 to 40 years were investigated in this randomized, cross-sectional study. Accommodation measurements in photopic luminance were taken for 6 m of empty field and for optotype fixation at 2 m, 1 m and 0.5 m. At scotopic luminance, dark focus of accommodation was examined directly after darkening and after 10 min of dark adaptation. After adaptation, subjects had to visualize imaginary targets in the four distances while accommodation was measured.

Interventions

DIAGNOSTIC_TESTAccommodation Measurement

Accommodation was measured for different distances and light conditions.

Sponsors

University of Applied Sciences Jena
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Masking description

Sequence of tests was randomized. It is no multi-arm study.

Eligibility

Sex/Gender
ALL
Age
22 Years to 39 Years
Healthy volunteers
Yes

Inclusion criteria

* age 18 - 44 * visual acuity at least 0.8 (5/6)

Exclusion criteria

* medication with an impact on the visual system * visual disease or disease with an impact on the visual system * pregnancy or other hormonal variances * drug usage * overfatigue at the period of investigation * mental handicap

Design outcomes

Primary

MeasureTime frameDescription
Shift of accommodation in scotopic luminance (Dark focus)Baseline onlyAccommodative shift in scotopic luminance compared to photopic luminance for empty field (dark focus of accommodation)

Secondary

MeasureTime frameDescription
Difference of accommodation for 2 m targetBaseline onlyAccommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 2 m
Difference of accommodation for 1 m targetBaseline onlyAccommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 1 m
Difference of accommodation for 0.5 m targetBaseline onlyAccommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 0.5 m

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026