Colonoscopy
Conditions
Keywords
Dietary fiber
Brief summary
This was a randomized, endoscopists' blinded comparison of bowel colonoscopy cleansing and tolerability of a prespecified low-residue diet compared with a clear liquid diet and Polyethylene Glycol bowel preparation. Outcome measures included efficacy of bowel preparation, patient preparation tolerability and side-effects.
Detailed description
An adequate examination is dependent on the bowel colonoscopy cleansing of stool. There are many different colon preparations, however endoscopists traditionally recommend the patient remain on a clear liquid diet for at least 24 h prior to their colonoscopy to reduce continued residue inflow into the colon from the small bowel, in addition the large volume preparation with PEG. The most common problems leading to less than adequate colon cleansing include lack of compliance with the clear liquid diet and difficulty taking the large volume preparation.
Interventions
DIETARY_SUPPLEMENTClear Liquid Diet
Clear liquid diet was compared with low-residue diet, in combination with Poliethylene Glycol in each group
DIETARY_SUPPLEMENTLow-residue Diet
Clear liquid diet was compared with low-residue diet, in combination with Poliethylene Glycol in each group
Sponsors
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Caregiver)
Masking description
This was a randomized, endoscopists' blinded comparison of bowel cleanising, tolerability and quality indicators for colonoscopy
Intervention model description
A total of 215 subjects were randomly assigned for this study, 105 in the clear liquid diet and 100 in the low residue-diet, 5 subjects were excluded in each group
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Out-patient scheduled for colonoscopy
Exclusion criteria
* Subjects under 18 years of age * Pregnancy * Subjects with decompensated metabolic, renal, cardiac and psychiatric disease * Allergy to PEG * Refuse participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of bowel colonoscopy preparation | 1 day | The quality of cleansing was recorded using the Boston Bowel Preparation Scale (BBPS), a four-point scoring system applied to each of the three broad regions of the colon (right=cecum and ascending, transverse= including the hepatic and splenic flexures and left=descending, sigmoid and rectum) during withdrawal. The point was assigned as 0= unprepared to 3=entire mucosa of colon segment seen well with no residual staining. Successful colon cleansing was considered when BBPS were \>2 per segment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Tolerability | 1 day | Patient tolerability was assessed using Viera scale (Likert), which measures the intensity of the symptoms related to the bowel preparation including nausea, vomiting, abdominal pain, abdominal distension and anal discomfort. The six-point scale ranging from 0-1=no complaints or some; 2-3=moderate and 4-5=severe symptoms. |
| Satisfaction | 1 day | Data on satisfaction were collected with a 1 to 10 visual analogue scale. Volume PEG consumed were evaluated as quartile (0%, 25%, 50%, 75% and 100%) prior colonoscopy. |
Outcome results
None listed