Inflammation and Steatosis: the Role of Alpha-defensin

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03358420

Enrollment

Registered

2017-11-30

Start date

2017-12-31

Completion date

2018-07-31

Last updated

2017-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatty Liver, Inflammation

Brief summary

The aim of this study is to examine the correlation between the severity of non-alcoholic steatohepatitis/non alcoholic fatty liver disease (NASH/NAFLD) in naïve and hepatitis C (HCV) positive patients and the amplitude of alpha-defensin immunohistochemical staining in liver biopsy.

Interventions

DIAGNOSTIC_TESTImmunohistochemical staining

Pathological liver slides to be immunohistochemically stained for alpha-defensin

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

15 Years to No maximum

Healthy volunteers

Inclusion criteria

* Fatty liver disease patients with liver biopsy

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame	Description
Amplitude of immunohistochemical stain	Six months	The amplitude of each slide will be graded from 1-4

Countries

Israel

Contacts

Primary ContactRami Abu Fanne, MD

ramia@hadassah.org.il972-50-3573694

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026