Cervical Spondylosis
Conditions
Keywords
Hybrid surgery,ACDF,C-ADR,bi-level cervical spondylosis
Brief summary
A muti-center study to compare the safety and efficacy of anterior cervical discectomy and fusion, cervical artificial disc replacement and hybrid surgery for bi-level cervical spondylosis.
Detailed description
Patients with bi-level cervical spondylosis undergoing anterior cervical discectomy and fusion, cervical artificial disc replacement and hybrid surgery in the muti-center hospital were retrospectively reviewed.The safety and efficacy were evaluated based on scores of the Neck Disability Index (NDI), visual analog scale (VAS), and Japanese Orthopedic Association (JOA) and the range of motion of both operative segments and adjacent segments,not only in the preoperative,but also in the 5 days,6 months,12 months and the 5 years after surgery.
Interventions
The patients undergoing anterior cervical discectomy and fusion sugery
PROCEDUREcervical artificial disc replacement
The patients undergoing cervical artificial disc replacement surgery
PROCEDUREhybrid surgery
The patients undergoing 1-level C-ADR plus 1-level ACDF surgery
Sponsors
Peking University People's Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* (1) Cervical degenerative pathology with symptomatic radiculopathy or myelopathy at two consecutive segments from C3 to C7 which not responding to conservative treatment for 6 weeks. (2) Preoperative magnetic resonance imaging (MRI), complete cervical spine radiography and computed tomography (CT) showed anterior compressive pathology. (3) None or slight osteophyte at the posterior edge of vertebrae. (4) None significant spinal stenosis or posterior compression.
Exclusion criteria
* ossification of the posterior longitudinal ligament (OPLL), tumor, fracture, infection, history of cervical spine surgery, narrowing of the spinal canal, and any serious general illness. Cases with one or more than two segments requiring treatment were also excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| range of the motion of operative segments and adjacent segments | preoperatively, within 5 days after surgery, and at 6, and 12 months postoperatively | Standard dynamic flexion and extension lateral cervical radiographs were obtained to evaluate range of motion of C2-C7 and operative segments and superior and inferior adjacent segments, cervical lordosis, and radiographic changes in adjacent segments. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| scores of the Japanese Orthopedic Association | preoperatively, within 5 days after surgery, and at 6, and 12 months postoperatively | Clinical effects were evaluated based on scores of the Japanese Orthopedic Association (JOA) |
| scores of the Neck Disability Index | preoperatively, within 5 days after surgery, and at 6, and 12 months postoperatively | Clinical effects were evaluated based on scores of the Neck Disability Index(NDI) |
| scores of the visual analog scale | preoperatively, within 5 days after surgery, and at 6, and 12 months postoperatively | Clinical effects were evaluated based on scores of the visual analog scale(VAS) |
Contacts
Primary ContactYU Guanjie, bachelor
Outcome results
None listed