Cancer, Energy Supply; Deficiency, Postoperative Complications, Surgery
Conditions
Brief summary
The role of nutritional therapy (TN) in the surgical patient is well described in the literature and is associated with reductions in postoperative complications, length of hospital stay, and mortality. Adequate determination of caloric and protein requirements is an essential step in the TN institution, avoiding hypoalimentation and hyperalimentation. Thus, it is essential to understand the changes in energy expenditure after surgery and its relation with nutritional status. In addition, little is known about the effect of nutritional therapy and caloric adequacy on parameters such as phase angle and dynamometry. Thus, the objective of this study is to evaluate the changes in energy expenditure after major abdominal surgeries and to evaluate the phase angle and dynamometry as possible markers of nutritional therapy. Energy expenditure will be assessed by indirect calorimetry. Functionality will be assessed by means of dynamometry and 6-minute walk test. Nutritional diagnosis will be given through subjective global assessment. Energy and protein intake will be monitored and registered daily. Phase angle will be obtained by performing bioelectrical impedance.
Interventions
None listed
Sponsors
Fundação de Amparo à Pesquisa do estado de Minas Gerais
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Federal University of Minas Gerais
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Over 18 years old * Patients admitted for major abdominal surgery * Sign the consent form
Exclusion criteria
* Length of hospital stay less than 3 days * Pregnancy * Patients who, for any reason, can not perform indirect calorimetry
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative complications | 30 days after surgery | According to the Dindo-Clavien protocol |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Phase angle | 24 hours pre-surgery, 3 and 7 days after surgery | Changes in phase angle after surgery as measured by bioelectrical impedance |
| Body composition | 24 hours pre-surgery, 3 and 7 days after surgery | Changes in body composition after surgery as measured by bioelectrical impedance |
| Nutritional status | 24 hours pre-surgery and 7 days after surgery | Changes in nutritional status after surgery as assessed by subjective global assessment (SGA) |
| Functional status | 24 hours pre-surgery, 3 and 7 days after surgery | Changes in functional status after surgery as assessed by hand grip strength |
| Energy expenditure | 3, 5 and 7 days after surgery | Changes in energy expenditure after surgery measured by indirect calorimetry |
Countries
Brazil
Contacts
Primary ContactMaria Isabel TD Correia, PHD
Backup ContactThales Antonio Silva
Outcome results
None listed