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Preoperative Corneal Thickness and Postoperative Visual Outcomes After Posterior Lamellar Corneal Transplant

Relationship Between Preoperative Corneal Thickness and Postoperative

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03355911
Acronym
TransCor
Enrollment
113
Registered
2017-11-28
Start date
2016-10-01
Completion date
2017-05-30
Last updated
2017-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal Changes of Membranes

Brief summary

To evaluate the impact of preoperative corneal thickness on visual outcomes following Descemet's stripping endothelial keratoplasty (DSAEK) or Descemet membrane endothelial keratoplasty (DMEK)

Detailed description

Patients underwent DSAEK or DMEK for endothelial dysfunction, from October 2013 to November 2016. Patients aged \> 18 years and with an indication for posterior lamellar graft surgery, such as Fuchs dystrophy, were included. Exclusion criteria included a history of penetrating keratoplasty in the study eye and a need for a penetrating keratoplasty following endothelial graft failure. Visual acuity, central corneal thickness (CCT) and graft thickness were measured preoperatively, and at postoperative day 7 and months 1, 3 and 6.

Interventions

None listed

Sponsors

Centre Hospitalier Régional Metz-Thionville
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Inclusion criteria

* Clinically indicated need for posterior lamellar graft surgery (DSAEK or DMEK) such as: * Fuchs dystrophy, * pseudophakic bullous decompensation * or other endothelial dysfunction corneal

Exclusion criteria

* were a history of penetrating keratoplasty in the indicated eye * the technical inability of preoperative CCT measurement * the need for a penetrating keratoplasty following endothelial graft failure * severe postoperative complications resulting in unquantifiable visual acuity

Design outcomes

Primary

MeasureTime frameDescription
Descemet's stripping endothelial keratoplasty (DSAEK) or Descemet membrane endothelial keratoplasty (DMEK)month 6LogMar

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026