Comparing Prognostic Performance of SEPSIS 2 and SEPSIS 3 Strategies at the Emergency Service

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03355833

Acronym

StraSEP

Enrollment

228

Registered

2017-11-28

Start date

2016-01-31

Completion date

2016-12-31

Last updated

2023-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Brief summary

In 2016, the Third International Consensus proposed a new strategy to screen aggravating risk in patients with septic shock. This strategy is based on quick-SOFA and the SOFA score. The main objective is to compare the prognostic performance of SEPSIS 3 against the previous strategy SEPSIS 2 to predict the admission in intensive care unit or the intra-hospital death.

Detailed description

This study compare the prognostic performance of two strategies. It's a monocentric, retrospective study in patients admitted to the emergency department.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Aged of 18 years or more * Initiation of one or more antibiotics in the Accident and Emergency Department in the Metz-Thionville hospital (CHR) site Mercy, for curative purpose, regardless of the infectious aetiology * Hospitalized in the CHR Metz-Thionville thereafter

Exclusion criteria

* Minors patients * Absence of antibiotic treatment initiated in the Emergency department * Prescription of antibiotic treatment in the emergency department for preventive purpose * Transferred by hospitalisation service of CHR Metz-Thionville in the emergency department * Absence of hospitalisation following their passage through the emergency department * Transferred to hospitalisation in an other establishment * Presence, at the admission, of an antibiotic treatment * Patients deceased in the emergency department

Design outcomes

Primary

Measure	Time frame	Description
Intrinsic and Extrinsic properties of SEPSIS 3 strategy	Day 1	The percentage of patients with high qSOFA score (2 or more) who were admitted in intensive care unit or who have died during their stay in hospital and rather the percentage of patients with a small qSOFA score who survived without passing through intensive care unit

Secondary

Measure	Time frame	Description
Correlation between lactate levels and mortality	Day 1	lactate levels at their admission

Outcome results