Use of MgSO4 for Pain After Bariatric Surgery

Use of MgSO4 Reduced Opioid Consumption for Pain After Sleeve Gastrectomy Operations: A Prospective Randomized Clinical Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03355807

Enrollment

Registered

2017-11-28

Start date

2017-01-01

Completion date

2017-12-15

Last updated

2018-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Therapeutic Opioid Induced Constipation (Disorder)

Keywords

sleeve gastrectomy, magnesium sulfate, postoperative pain, bariatric surgery

Brief summary

The purpose of this study was to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation

Detailed description

The purpose of this study is to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation. Design: A prospective, randomized, controlled clinical study. Setting: University hospital. Participants: Eighty patients undergoing sleeve gastrectomy. Measurements and Main Results: Visual analog scale for pain score, sedation score, mean arterial pressure, heart rate, and valid and invalid analgesic demand will record. Serum magnesium levels will determined at preoperative evaluation, postanesthesia care unit admission and at 24 hours. Side effects will also record.

Interventions

DRUGMagnesium

The magnesium group (group Mg, n \_ 40) received an additional infusion of MgSO4

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Masking description

A Patient, investigator and anesthesiologist who was blinded to the assignment of the patients recorded levels of sedation, pain, cumulative morphine consumption, and hemodynamic variables

Intervention model description

The patients undergoing sleeve gastrectomy.

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* 18 to 65 year old individuals who underwent laparoscopic sleeve gastrectomy.

Exclusion criteria

* One or more of the following: cardio - vascular and respiratory diseases, drug and/or alcohol abuse, use of daily an algesia 24 hours before the surgery, renal failure, and liver dysfunction.

Design outcomes

Primary

Measure	Time frame	Description
Item pain intensity measure assessed by using VAS scores	1 day	Pain was assessed by using VAS scores (0: no pain and 10: worst pain) imaginable recorded at 0, 1, 2, 4, 6, 24, and 24 hours.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026