Obesity, Physical Fitness
Conditions
Brief summary
The Quebec Family Study (QFS) is an observational study that was planned to investigate the role of genetic factors in physical fitness, body composition, risk factors for common disease and health-related behaviour.
Detailed description
The Quebec Family Study was an observational study with three cycles of data collection between 1978 and 1992. During the first cycle of data collection (Phase 1: 1978-1982), a total of 1,650 subjects from 375 families were recruited. During the second cycle (Phase 2: 1989-1997), 385 subjects from 105 phase 1 families were retested and an additional 372 subject from 74 families were recruited. During the third cycle (Phase 3: 1998-2002), 204 subjects from phase 1 were tested a third time, 113 subjects from phase 2 were tested a second time and 194 new subjects from 44 families were recruited.
Interventions
None listed
Sponsors
Canadian Institutes of Health Research (CIHR)
Louis Pérusse
Study design
Observational model
FAMILY_BASED
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
10 Years to No maximum
Inclusion criteria
* Age over 10 years
Exclusion criteria
* Not applicable
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body composition | Through study completion, an average of 24 years | Body composition as assessed by underwater weighing |
| Body mass index (kg/m^2) | Through study completion, an average of 24 years | Body mass index assessed from height and weight |
| Abdominal fat | Through study completion, an average of 24 years | Abdominal fat as assessed by commuted tomography |
| Waist and hip circumferences (cm) | Through study completion, an average of 24 years | Waist and hip circumferences (cm) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Physical activity level | Through study completion, an average of 24 years | Physical activity level assessed by questionnaire |
| Blood pressure (mm Hg) | Through study completion, an average of 24 years | Systolic and diastolic blood pressure |
| Plasma lipid levels (mmol/L) | Through study completion, an average of 24 years | Fasting levels of triglycerides, LDL-cholesterol and HDL-cholesterol in mmo/L |
| Glucose levels (mmol/L) | Through study completion, an average of 24 years | Plasma glucose levels in a fasting state and following an oral glucose tolerance test, inflammatory markers. Plasma glucose levels in a fasting state and during an oral glucose tolerance test |
| Insulin levels (pmol/L) | Through study completion, an average of 24 years | Plasma insulin levels in a fasting state and following an oral glucose tolerance test. |
| Alcohol consumption | Through study completion, an average of 24 years | Alcohol consumption (nb of drinks per week) |
| Adiponectin levels (in micrograms/ml) | Through study completion, an average of 24 years | Adiponectin levels (in micrograms/ml) |
| Interleukin-6 (IL6) and tumor necrosis factor-alpha (TNF-alpha) in pg/ml | Through study completion, an average of 24 years | Interleukin-6 (IL6) and tumor necrosis factor-alpha (TNF-alpha) in pg/ml |
| Smoking habits (nb of cigarettes per day) | Through study completion, an average of 24 years | Smoking habits (nb of cigarettes per day) |
| Sleeping (hours/day) | Through study completion, an average of 24 years | Sleeping (hours/day) |
| C-reactive protein (CRP in mg/ml) | Through study completion, an average of 24 years | C-reactive protein (CRP in mg/ml) |
| Caloric intake | Through study completion, an average of 24 years | Total caloric intake and macronutrient intake using a 3-day dietary record |
| Eating behaviour | Through study completion, an average of 24 years | Eating behaviour assessed using the Three-Factor Eating questionnaire |
| Energy expenditure | Through study completion, an average of 24 years | Oxygen consumption at rest and during exercise |
Outcome results
None listed