Colorectal Adenoma, Colorectal Polyp
Conditions
Keywords
Colonoscopy, Lower Gastrointestinal Tract, Re-examination, Retroflexion
Brief summary
The primary aim of this study is \- to explore the usefulness of re-examination and retroflexion on adenoma miss rate (AMR) in the proximal colon. Other aims include to explore the data below when re-examination or retroflexion is used. * Adenoma detection rate, ADR * Polyp miss rate, PMR * Polyp detection rate, PDR * Withdrawal time, WT
Detailed description
AMR = number of adenomas missing during the first examination/ total number of adenomas in both examinations = number of adenomas detected only in the second examination/(number of adenomas detected during the first examination + number of adenomas detected only in the second examination)
Interventions
PROCEDURERetroflexion
Retroflexion technique in colonoscopy means turning the colonoscope tip 180 degree in order to look backward in the colon and rectum.
PROCEDURERe-examination
Re-examination in colonoscopy means examining the cecum and ascending colon twice in the routine fashion.
Sponsors
Changhai Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
45 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients between 45 and 80 years who undergo colonoscopy examination for screening, and who receive primary screening and get positive result
Exclusion criteria
* Pregnant female patients * Patients received colonoscopy in the past 5 years * Patients who have history of colorectal cancer, colorectal polyposis, inflammatory bowel disease or heredity colorectal neoplasm syndrome such as familiar adenomatous polyposis, Lynch Syndrome and so on * Patients who had previous abdominal surgery * Patients who are known to have colonic stricture or obstructing tumor from the results of radiography (X ray, CT scan or barium enema) * Patients who are presenting acute surgical conditions such as severe colitis, megacolon and active gastrointestinal bleeding * Patients who have inadequate bowel preparation * Patients who reject to participate in this study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Adenoma miss rate in the proximal colon (AMR) | At the end of the procedure, up to 1 hour | AMR refers to the rate of adenoma missing, calculated as the proportion of adenomas which are missing in the first examination. AMR in the proximal colon is calculated with only the proximal colon concerned. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adenoma Detection Rate in the proximal colon (ADR) | At the end of the procedure, up to 1 hour | ADR refers to the rate of adenoma detection, calculated as the proportion of subjects with at least one adenoma. ADR in the proximal colon is calculated with only the proximal colon concerned. |
Countries
China
Contacts
Primary ContactEn-Da YU, MBBS
Backup ContactZi-Ye ZHAO, MD
Outcome results
None listed