Endometriosis and Risk of Obstetric Complications

Impact of Endometriosis on the Risk of Obstetric Complications in Spontaneous Pregnancy: a Multicentric Italian Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03354793

Enrollment

844

Registered

2017-11-28

Start date

2016-01-15

Completion date

2017-10-04

Last updated

2017-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis, Pregnancy Complications

Brief summary

The aim of this study is to compare the rate of obstetric complications at first spontaneous pregnancy among women with endometriosis, with the rate of obstetric complications at first spontaneous pregnancy among women without endometriosis

Detailed description

All women followed up for a surgical or clinical/sonographic diagnosis of endometriosis in 11 italian referral Centres for the treatment of endometriosis, completed a questionnaire regarding their previous pregnancies. The same questionnaire was completed by women, attending a routine gynecologic visit, in whom surgery or clinical/sonographic evaluation excluded endometriosis.

Interventions

OTHERSurvey on first pregnancy after endometriosis diagnosis

Obstetric complications were noted

OTHERSurvey on first pregnancy

Obstetric complications were noted

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

30 Years to 50 Years

Inclusion criteria

* 30 to 50 years old women with at least one previous spontaneous pregnancy \> 12 weeks with surgical or clinical/sonographic diagnosis of endometriosis or in whom surgical or clinical/sonographic evaluation ruled out endometriosis

Exclusion criteria

* Pregnancy achieved by assisted reproductive techniques * Pregnancy terminated before 12 gestational weeks * Twin pregnancy * Preexisting hypertension * Lupus like anti-coagulant * Non corrected uterine malformation * Recurrent abortion

Design outcomes

Primary

Measure	Time frame	Description
Pre-term delivery	2 years	comparison of rate of preterm delivery in the two groups

Secondary

Measure	Time frame	Description
Placenta praevia	2 years	comparison of rate of placenta praevia in the two groups

Other

Measure	Time frame	Description
Intra uterine Growth Restriction	2 years	comparison of rate of IUGR fetuses in the two groups
HELLP syndrome	2 years	comparison of rate of HELLP syndrome in the two groups

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026