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Endometriosis and Risk of Miscarriage

Impact of Endometriosis on the Risk of Miscarriage in Spontaneous Pregnancy: a Multicentric Italian Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03354780
Enrollment
844
Registered
2017-11-28
Start date
2016-01-15
Completion date
2017-10-04
Last updated
2017-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis, Miscarriage

Brief summary

The aim of this study is to compare the rate of miscarriage at first spontaneous pregnancy among women with endometriosis with the rate of miscarriage at first spontaneous pregnancy among women without endometriosis.

Detailed description

All women followed up for a surgical or sonographic diagnosis of endometriosis in 11 italian referral Centres for the treatment of endometriosis completed a questionnaire regarding their previous pregnancies. The same questionnaire was completed by women, attending a routine gynecologic visit, in whom surgery or vaginal examination and pelvic ultrasonography excluded endometriosis.

Interventions

rate of miscarriage was noted

Sponsors

University of Milan
CollaboratorOTHER
Endometriosis Treatment Italian Club
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
30 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* 30 to 50 years old women * with at least one previous spontaneous pregnancy * with surgical or clinical/sonographic diagnosis of endometriosis or * in whom surgical or clinical/sonographic evaluation ruled out endometriosis

Exclusion criteria

* Pregnancy achieved by Assisted Reproductive technology * Biochemical pregnancy * Non corrected uterine malformation, poliabortivity, lupus like anticoagulant

Design outcomes

Primary

MeasureTime frameDescription
Rate of miscarriage2 yearscomparison of rate of miscarriage in the two groups

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026