Furcation Defects
Conditions
Keywords
Mandibular type II furcations, Periodontal treatment, Demineralized bovine bone mineral, Collagen membrane
Brief summary
The aim of the study was to perform a randomized controlled clinical study in order to compare the effects of a bovine derived xenograft (with 10% collagen) + a bioabsorbable membrane (control group, CG) vs a bovine derived xenograft (with 10% collagen) alone (test group, TG) on the surgical treatment of mandibular type II furcation defects.
Detailed description
The aim of the study was to perform a randomized controlled clinical study in order to compare the effects of a bovine derived xenograft (with 10% collagen) + a bioabsorbable membrane (control group, CG) vs a bovine derived xenograft (with 10% collagen) alone (test group, TG) on the surgical treatment of mandibular type II furcation defects. The patients all underwent the same surgical intervention with the only difference between the two groups being the use or not of a collagen membrane.
Interventions
PROCEDUREOpen flap surgery
Elevation of a flap in order to access the treated furcation
DEVICEBio-oss collagen
Biomaterial for periodontal surgery
DEVICEBio-gide
Biomaterial for periodontal surgery
Sponsors
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
The patients didn't know whether they were the control or test group
Intervention model description
Randomized clinical study with 1 control group and 1 test group
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients diagnosed with chronic periodontitis * Initial phase (oral hygiene instructions + full mouth scaling and root planing) performed at least eight weeks before inclusion * Full-mouth plaque score ≦ 20% (at least eight weeks after initial phase and during the whole treatment) * Clinical evidence of vestibular or lingual mandibular Class II furcation defects (≧ 3mm of horizontal probing depth) * Presence of at least 2 mm of keratinized gingiva on the selected tooth surface facing the furcation * Tooth vitality confirmed by clinical tests (cold testing)
Exclusion criteria
* Presence of any systemic disease * Smokers * Devitalized tooth or tooth presenting periapical or pulpar pathology (confirmed with a retro-alveolar radiograph) * Allergies to any of the products used in the present study * Pregnant or breastfeeding women * History or current RX therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Horizontal Probing Attachment Level | 6 months | PAL-H |
Outcome results
None listed