Inmediate Feeding Tolerance in Acute Pancreatitis

Inmediate Feeding Tolerance in Patients With Mild and Acute Biliary Pancreatitis vs Early Feeding

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03354065

Enrollment

Registered

2017-11-27

Start date

2017-01-01

Completion date

2017-08-31

Last updated

2017-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pancreatitis Due to Gallstones

Keywords

pancreatitis, mild, biliary, referring

Brief summary

Objective: Determine tolerance of immediate oral intake (8 hours posterior to the beginning of treatment) against traditional management (early feeding at 48hr) in patients with mild acute pancreatitis of biliary origin. Double blind, randomized clinical trial

Detailed description

The investigators included patients 15 - 85 years old, any sex. Diagnosis of mild acute pancreatitis according to the Ranson, APACHE II and BISAP. Signed infromed consent to participate in the study. All participants had a hepatic and biliary ultrasound to determine the biliary etiology. The investigators excluded patients with pancreatitis of nonbiliary etiology, pregnant, severe pancreatitis, cholangitis or choledocholithiasis demonstrated during the hospital stay or with other comorbidities.

Interventions

DIETARY_SUPPLEMENTTIME OF FEEDING

Liquid ( Re Feeding 8 h ) OR Enteral Feeding ( re feeding 48 h)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Masking description

blinding of the evaluator to the study group blinding of patient to study hypothesis

Eligibility

Sex/Gender

ALL

Age

15 Years to 85 Years

Healthy volunteers

Inclusion criteria

Patients older than 15 years. * Patients with a diagnosis of mild acute pancreatitis biliary. * Patients who agree to enter the protocol.

Exclusion criteria

* Patients managed at another institution. * Patients with a diagnosis of pancreatitis of non-biliary etiology. * Patients with heart disease or lung disease. * Patients with organic failure. * Patients with pregnancy. * Patients with cholangitis.

Design outcomes

Primary

Measure	Time frame	Description
Pancreatitis reactivation after oral Feeding	Measures at 24hours after the begining of the oral intake	Resurgence of characteristically epigastric tansfictive pain, irradiated to the left, upper quadrant region after beginning the oral intake, systemic inflammatory response syndrome ( C reactive protein) or Significant leucocyte elevation

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026