Coronary Artery Disease, Percutaneous Coronary Intervention
Conditions
Keywords
Percutaneous coronary intervention, antiplatelet, platelet function, prognosis
Brief summary
To identify the optimal cut-off values in different platelet function testing to predict MACCE at 12-months in complex PCI patients of China
Detailed description
This study will observe the relationship between platelet function testing and clinical outcomes. Meanwhile we aim to identify optimal cut-off values in different platelet function testing, including IPF, TEG and VerifyNow, to predict MACCE during12-months in complex PCI patients.
Interventions
None listed
Sponsors
Chinese Academy of Medical Sciences, Fuwai Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Documented undergoing complex PCI in 1 year prior to enrollment.
Exclusion criteria
* Presence of any condition/circumstance which in the opinion of the investigator could significantly limit the complete follow up of the patient (e.g. tourist, non-native speaker or does not understand the local language where interpreter services are not reliably available, psychiatric disturbances, alcohol or drug abuse). * Presence of serious/severe co-morbidities in the opinion of the investigator which may limit life expectancy (\<1 year). * Current participation in a blinded randomized clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Optimal cut-off values in different platelet function testing to predict MACCE at 12-months in complex PCI patients of China | Within 12 months of patient enrolled |
Secondary
| Measure | Time frame |
|---|---|
| Effectiveness and sensitivity of predicting between different platelet function testing | Within 12 months of patient enrolled |
Countries
China
Contacts
Primary ContactChunli Shao, MD
Outcome results
None listed