Infertility
Conditions
Brief summary
The purpose of this study is to investigate the impact of follicular flushing on fertilization rate in women undergoing IVF treatment
Detailed description
This will be a prospective observational study on the effect of follicular flushing on fertilization rate in women undergoing IVF treatment. Oocytes from each woman will be allocated to one of three groups, depending on the aspirate or flush they are recovered from: Group I= egg retrieved in the follicular fluid of the first aspirate (no flushing) Group II= egg retrieved in the 1st-2nd flush Group III= egg retrieved in the 3rd-5th flush development and utilization. Pregnancy rates will be reported as a surrogate outcome.
Interventions
All eggs will be fertilized by ICSI
Sponsors
Eugonia
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Inclusion criteria
* Up to 40 years old * Both ovaries present * Triggering final oocyte maturation using hCG or GnRH agonist
Exclusion criteria
* Egg donation * PGD cases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fertilization rate | Day 1 post oocyte retrieval | Number of fertilized eggs per oocyte retrieved |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Maturation rate | Day of oocyte retrieval | Number of mature (MII) eggs per oocyte retrieved |
| Good quality embryos | Day 2 post oocyte retrieval | Number of good quality embryos on Day 2 |
| Blastocyst formation rate | Day 5 post oocyte retrieval | Number of blastocysts on Day 5 per fertilized egg |
Countries
Greece
Contacts
Primary ContactTryfon G Lainas, PhD
Backup ContactGeorge T Lainas, MD
Outcome results
None listed