Fructose Metabolism Disorder
Conditions
Brief summary
Diabetes is one of the most common and chronic diseases in the world, with the prevalence and incidence of this disease rising in most societies, especially in Iran. Suitable treatments for type 2 diabetes include changing lifestyle with exercise, nutrition, and drug use. New research suggests that added sugar, especially fructose, is the main trigger for diabetes and pre-diabetes even more potent than other carbohydrates. Fructose has a low glycemic index (23μg =) and slowly increases blood glucose levels. Therefore, it is thought that replacing fructose instead of glucose can have a positive effect on glycemic control of diabetic patients..
Interventions
OTHERlow frutose diet
Sponsors
National Nutrition and Food Technology Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
40 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. Age of 70-40 years 2. body mass index(BMI) between 18.5 and 27 3. Type 2 diabetes People who only control their diabetes by using glucose lowering tablets Type 2 diabetes (1 to 10 years)
Exclusion criteria
1. Pregnancy and lactation 2. Thyroid gland disorders 3. Kidney disease and inflammation 4. Follow the weight loss regimen 6 months before starting the study 5. Usage of fatty and fatty foods, fiber powder Vitamin A Mineral Supplements, Omega 3 6. Taking glucocorticoid drugs and non-steroidal anti-inflammatory drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fasting blood suger(FBS) | 8 weeks |
| Homeostatic model assessment and insulin resistance(HOMA-IR) | 8weeks |
| insulin | 8 weeks |
Secondary
| Measure | Time frame |
|---|---|
| HDL-C | 8 weeks |
| Triglyceride | 8 weeks |
| Blood pressure | 8 weeks |
| Total cholestrole | 8 weeks |
| LDL-C | 8 weeks |
Outcome results
None listed