Estimation of Perioperative Atelectasis

A Comparison Between Two Methods for Estimating the Extent of Perioperative Atelectasis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03352336

Enrollment

Registered

2017-11-24

Start date

2017-12-04

Completion date

2018-08-28

Last updated

2018-10-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atelectasis, Oxygenation

Keywords

Atelectasis, Oxygenation, Venous admixture, Computed Tomography, Oxygenation test

Brief summary

This study will compare an oxygenation test based on arterial blood gas analysis with computed tomography for estimating the extent of atelectasis.

Detailed description

Computed tomography of the lungs is the gold standard for investigating the extent of atelectasis, which is common in the perioperative setting. Atelectasis increase the risk of postoperative pulmonary complications and result in pulmonary shunt, which is one of the two major causes of impaired oxygenation. The other cause is admixture of venous blood from poorly ventilated regions of the lungs. The investigators have developed an oxygenation test utilizing arterial blood gas analysis at different inspired fractions of oxygen, which may be used to distinguish between these two causes. This observational study aims to establish the agreement between computed tomography and the oxygenation test for estimating the extent of atelectasis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 75 Years

Inclusion criteria

* American Society of Anesthesiology (ASA) class I-II. * Non-abdominal day case surgery under general anesthesia. * Patients enrolled in study registered in ClinicalTrials with NCT ID.

Exclusion criteria

* Arterial oxygen saturation (SpO2) \<90 % with 40% Venturi mask. * Unstable postoperative condition needing immediate treatment.

Design outcomes

Primary

Measure	Time frame	Description
Atelectasis area	30 min after emergence from anesthesia	Atelectasis area as studied by computed tomography

Secondary

Measure	Time frame	Description
Pulmonary shunt estimated by a standardised oxygenation test	30 min after emergence from anesthesia	Pulmonary shunt estimated by a standardised oxygenation test using

Countries

Sweden

Outcome results