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Nanofat in Post Burn Scars on the Face

Rejuvenation of Post Burn Scars on the Face With Unfiltered Nanofat Injection

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03352297
Enrollment
48
Registered
2017-11-24
Start date
2016-01-01
Completion date
2016-12-31
Last updated
2017-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn Scar

Keywords

Post burn scar face, Unfiltered nanofat, Adipose tissue growth factors, Adipose stem cells, POSAS, Image J, Face

Brief summary

Quasi-Experimental Study: Unfiltered Nanofat Injected into Postburn Facial Scars Number of Patients: 48 Outcome Assessed on POSAS And with Imaje J Scanning Preop And Postop Statistical Comparison of Scar Done

Detailed description

Objective: To compare the quality of post burn facial scars before and after injection of unfiltered nanofat. Place and Duration of Study: Plastic Surgery Department, Mayo Hospital, Lahore, from January 2016 to December 2016. Methodology: 48 patients with post burn facial scars were included, age range 4 to 32 years with Fitzpatrick skin types between 3 and 4. Patients with hypertrophic scars, contractures or keloids were excluded. Scars were assessed by a senior plastic surgeon and the patient on the POSAS. Fat was harvested from the abdomen and/or thighs with a 3 mm multi-port liposuction cannula (containing several sharp side holes of 1 mm) using Coleman's technique, emulsified, and transferred into 1 ml Leur lock syringes for injection into the subdermal or intradermal plane. Final follow up was scheduled at 6 months and scar was rated by the patient and the same surgeon on the POSAS. Pre and post op scar scores were compared and p-values calculated.

Interventions

BIOLOGICALUnfiltered Nanofat Graft

Nanofat created from microfat, skipping the filtration step. Intradermal and subdermal injections in post burn scars on the face.

Sponsors

King Edward Medical University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Post burn scars on the face * Fitzpatrick skin types between 3 and 4

Exclusion criteria

* Hypertrophic scars * Contractures * Keloids

Design outcomes

Primary

MeasureTime frameDescription
Rejuvenation of post burn scars on the face with unfiltered nanofat injection1 yearPre and post-operative POSAS score

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026