Delirium
Conditions
Brief summary
Delirium is the most common neurological complication of cardiac surgery patients and associated with poor prognosis. In recent years, the important role of quantitative electroencephalogram (qEEG) in brain function monitoring is becoming increasingly prominent. The purpose of this study is to evaluate the effect of qEEG in predictive of post-operation delirium and prognosis of cardiac surgery patients.
Interventions
DEVICEquantitative electroencephalogram (qEEG)
the patients receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU
Sponsors
Southeast University, China
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
1. The patients of cardiac surgery aged ≥18 years 2. Signed informed consent
Exclusion criteria
1. Patients with a history of any neurologic and psychiatric disease 2. Cognitive disorder 3. Stroke history in three years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| amplitude integrated electroencephalogram (aEEG) | 24 hours | the electroencephalogram amplitude of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| alpha frequency band energy | 24 hours | the percentage of alpha frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit |
| beta frequency band energy | 24 hours | the percentage of beta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit |
| theta frequency band energy | 24 hours | the percentage of theta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit |
| delta frequency band energy | 24 hours | the percentage of delta frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit |
| alpha variability | 24 hours | the variability of alpha frequency band of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit |
| arterial oxygen saturation (SaO2) | 24 hours | the level of arterial oxygen saturation (SaO2) of cardiac surgery patients when admitted to intensive care unit |
| central venous oxygen saturation (ScvO2) | 24 hours | the level of central venous oxygen saturation(ScvO2) of cardiac surgery patients when admitted to intensive care unit |
| neuron specific enolase (NSE) | 24 hours | the level of neuron specific enolase (NSE) of cardiac surgery patients when admitted to intensive care unit |
| interleukin-6 (IL-6) | 24 hours | the level of interleukin-6 (IL-6) of cardiac surgery patients when admitted to intensive care unit |
| troponin i (TNI) | 24 hours | the level of troponin i (TNI) of cardiac surgery patients when admitted to intensive care unit |
| high-sensitivity C-reactive protein (hs-CRP) | 24 hours | the level of high-sensitivity C-reactive protein (hs-CRP) of cardiac surgery patients when admitted to intensive care unit |
| N-terminal pro brain natriuretic peptide (NT-pro-BNP) | 24 hours | the level of N-terminal pro brain natriuretic peptide (NT-pro-BNP) of cardiac surgery patients when admitted to intensive care unit |
Contacts
Primary ContactLiu Wenxue, master
Backup ContactYang Congshan, professor
Outcome results
None listed