Ewha Birth and Growth Study (Birth Cohort)

Evaluation of Influencing Factors Affecting Childhood Metabolic Indicators in Korea (Repeated Measures Analysis; Longitudinal Birth Study)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03351595

Enrollment

734

Registered

2017-11-24

Start date

2001-09-30

Completion date

2020-07-31

Last updated

2017-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Health

Keywords

Growth pattern, Environmental and prenatal exposure

Brief summary

Ongoing longitudinal birth cohort established at Mok-dong Hospital, Ewha Woman's University, Seoul, South Korea, between 2001 and 2006.

Detailed description

Cohort composed of mothers, who visited to prenatal care between 24 and 28 weeks of gestation, between 2001 and 2006. After the child was born then, we collected information at birth outcome and conducted mail surveys at 6, 12, 18, and 24 months. Regular check-up was conducted at 3, 5, and every year after 7 years of age(last check up point: 15 years old). In check-up survey, after an 8-hour overnight fast, blood and urine samples (3 ml EDTA-blood and 5 ml serum) were obtained from subjects by venepuncture. following parameters were checked: physical growth, blood pressure. metabolic biomarker(Total cholesterol, HDl-cholesterol, TG(triglyceride), glucose, uric acid, etc.), K-CBCL(Korea-child behavior checklist), 24 hour recall method for nutrition, FFQ(Food Frequency Questionnaire), Questionnaires including Socio-economic status and physical activity.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

24 Weeks to 17 Years

Healthy volunteers

Yes

Inclusion criteria

* Participants' mothers, who visited to prenatal care between 24 and 28 weeks of gestation. * An individual who can be followed up during the study period and is capable of complying with the study requirements

Exclusion criteria

* An individual thought to have difficulty participating in the study due to other reasons, based on the judgment of the investigator

Design outcomes

Primary

Measure	Time frame	Description
Profile of participants received regular medical check-up and result feed back for growth development	365days	Changes from baseline in physical growth using anthropometric measurement

Secondary

Measure	Time frame	Description
Profile of participants received blood pressure measurement for pediatric hypertension	365days	Changes from baseline in average blood pressure(mmHg, diastolic and systolic) as above the 95th percentile adjusted for sex, age, and height percentile

Outcome results