Optimizing the Efficiency and Implementation of Cash Transfers to Improve Adherence to Antiretroviral Therapy

Conditions

Adherence, Medication, Adherence, Patient, HIV/AIDS

Brief summary

1. Determine the dose-response relationship between a cash transfer amount and HIV viral suppression at 6 months 2. Identify the most effective cash transfer size to increase the proportion of people living with HIV infection (PLHIV) retained in care and with suppressed viral load (\<1000 copies/ml) after 6 months. (This amount will be further evaluated in a cluster randomized trial in Phase 2).

Detailed description

Participants in the control group will receive the standard HIV primary care services according to Tanzania's National Guidelines for the Management of HIV and AIDS. The study has two active intervention arms: 1. The opportunity to earn 10,000 TZS/month (\ $4.50) for up to 6 months conditional on visit attendance, and 2. The opportunity to earn 22,500 TZS/month (\ $10.00) for up to 6 months conditional on visit attendance In both intervention arms, cash transfers will be delivered a maximum of once monthly, spaced ≥28 days apart, for up to six months and delivered via an automatic mobile money system linked to a biometric identification system.

Winters S, Sabasaba A, Fahey CA, Packel L, Katabaro E, Ndungile Y, Njau PF, McCoy SI.

2023-06-105 citations

10.1186/s12981-023-00534-y

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Packel L, Fahey C, Kalinjila A, Mnyippembe A, Njau P, McCoy SI.

2021-09-2310 citations

10.1186/s43058-021-00214-w

Optimizing the efficiency and implementation of cash transfers to improve adherence to antiretroviral therapy: study protocol for a cluster randomized controlled trial

Laura Packel, Prosper Njau, Carolyn A. Fahey, Angela Ramadhani, William H. Dow et al. (7 authors)

Trials2020-11-2312 citations

10.1186/s13063-020-04899-7

Financial incentives to promote retention in care and viral suppression in adults with HIV initiating antiretroviral therapy in Tanzania: a three-arm randomised controlled trial.

Fahey CA, Njau PF, Katabaro E, Mfaume RS, Ulenga N, Mwenda N, Bradshaw PT, Dow WH, Padian NS, Jewell NP, McCoy SI.

2020-09-0361 citations

10.1016/s2352-3018(20)30230-7

Interventions

BEHAVIORALActive Arm 1

Participants in this arm will receive the standard HIV primary care services according to Tanzania's National Guidelines for the Management of HIV and AIDS plus the opportunity to earn 10,000 TZS/month conditional on visit attendance.

BEHAVIORALActive Arm 2

Participants in this arm will receive the standard HIV primary care services according to Tanzania's National Guidelines for the Management of HIV and AIDS plus the opportunity to earn 22,500 TZS/month conditional on visit attendance.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE (Subject)

Masking description

Participants in the cash transfer arms will be masked to the knowledge that there are two cash value arms.

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* ≥18 years * Living with HIV infection * Initiated antiretroviral therapy ≤1 month prior to enrollment in the study

Exclusion criteria

\- Participants who do no provide informed consent

Design outcomes

Primary

Measure	Time frame	Description
HIV viral suppression at 6 months	6 months	\<1000 copies/ml

Countries

Tanzania

Outcome results

None listed