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Healthful Diets and Risk of Hearing Loss

Healthful Dietary Patterns and Risk of Hearing Loss in Women

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03351023
Enrollment
70966
Registered
2017-11-22
Start date
1991-07-01
Completion date
2013-06-30
Last updated
2017-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hearing Loss

Brief summary

To prospectively examine the relations between adherence scores for three healthful dietary patterns, the Alternate Mediterranean diet (AMED), the Dietary Approaches to Stop Hypertension (DASH), and the Alternative Healthy Eating Index (AHEI-2010), and risk of hearing loss in the Nurses' Health Study II.

Interventions

OTHERno intervention-this was an observational study

Sponsors

Brigham and Women's Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
27 Years to 66 Years

Inclusion criteria

* The investigators limited the study to women who provided information on their hearing on the 2009 or 2013 questionnaire.

Exclusion criteria

* The investigators excluded those who did not provide responses to the hearing questions on either questionnaire, reported a hearing problem that began before baseline for the current analysis (1991) or did not report date of onset, or reported cancer other than non-melanoma skin cancer. The investigators also excluded women who did not complete the baseline diet questionnaire and who had missing diet information for each subsequent time period.

Design outcomes

Primary

MeasureTime frameDescription
Hearing loss1991-2013The primary outcome, self-reported hearing loss that was moderate or worse in severity, was determined based on responses to the 2009 and 2013 questionnaires on which participants were asked about their hearing. On the 2009 main questionnaire, participants were asked, Do you have a hearing problem? (no, mild, moderate, severe), and At what age did you first notice a change in your hearing? On the 2013 main questionnaire, participants were asked, Which best describes your hearing? (excellent, good, a little hearing trouble, moderate hearing trouble, deaf), and Have you noticed a change in your hearing? and, if the response was Yes, At what age did you first notice a change in your hearing?

Secondary

MeasureTime frameDescription
hearing loss in HSSQ1991-2013Detailed hearing-related information was collected electronically in 2012 supplemental questionnaire from a representative subcohort of NHS II participants (n= 33,102) with and without reported hearing problems, including information on previous evaluation for hearing loss, laterality (unilateral or bilateral), and identified causes of hearing loss (e.g. ototoxic medications, ear trauma, otosclerosis, cholesteatoma, Meniere's disease, chronic ear infection). Data from the HSSQ were used to conduct sensitivity analyses using more refined case definitions (e.g. excluding known etiologies and unilateral hearing loss).

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026