Skin Problems
Conditions
Brief summary
Previous studies on skin health with Lactic acid bacteria (LAB) have been published for many years, including prevention of skin diseases and improvement of skin conditions. In this clinical study, the investigators researched the benefit effects of heat-killed Lactobacillus plantarum cream on skin health.
Detailed description
To evaluate the efficacy of applying probiotic cream in the ameliorationof the whole face skin conditions such as moisturizing, whitening, anti-wrinkle and so on.
Interventions
COMBINATION_PRODUCTEmulsion base with probiotics
Water、Polyglyceryl-3/ Methylglucose Distearate、Triethyl Hexanoin、Macadamia Ternifolia Seed Oil、Propanediol、PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin、Cetyl Alcohol、Myristyl Myristate、Glycerin、Glycosyl Trehalose/Hydrogenated Starch Hydrolysate、Rice Ferment Filtrate(Sake)、Saccharomyces/Daylily Flower Ferment Filtrate、Bis-PEG/PPG-20/5 PEG/PPG-20/5Dimethicone、Methoxy PEG/PPG-25/4 Dimethicone、Caprylic/Capric Triglyceride、Sodium Polyacrylate、Phenoxyethanol、o-Cymen-5-ol、Xanthan Gum、Potassium Hydroxide, Heat-killed L. plantarum powders (1x10\^9 cells/ g-cream)
OTHEREmulsion base
Water、Polyglyceryl-3/ Methylglucose Distearate、Triethyl Hexanoin、Macadamia Ternifolia Seed Oil、Propanediol、PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin、Cetyl Alcohol、Myristyl Myristate、Glycerin、Glycosyl Trehalose/Hydrogenated Starch Hydrolysate、Rice Ferment Filtrate(Sake)、Saccharomyces/Daylily Flower Ferment Filtrate、Bis-PEG/PPG-20/5 PEG/PPG-20/5Dimethicone、Methoxy PEG/PPG-25/4 Dimethicone、Caprylic/Capric Triglyceride、Sodium Polyacrylate、Phenoxyethanol、o-Cymen-5-ol、Xanthan Gum、Potassium Hydroxide
Sponsors
Chia Nan University of Pharmacy and Science
GenMont Biotech Incorporation
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Randomized, Parallel, Open Label Study
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy volunteers between the ages of 20-60.
Exclusion criteria
* Subjects with photosensitivity (Sun allergy). * Subjects are undergoing medical therapy for skin diseases. * Subjects with severe hyperpigmentation. * Subjects with diabetes. * Subjects with cosmetics allergy. * Subjects who have recently participated laser therapies or other treatments are not suitable for sun.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Skin Diagnosis | Baseline, 4 weeks and 8 weeks | The changes of skin condition by VISIA Complexion Analysis System |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Skin Moisture | Baseline, 4 weeks and 8 weeks | The changes of skin moisture by Skicon-200EX and Corneometer CM 825 |
| Skin Color | Baseline, 4 weeks and 8 weeks | The changes of skin color by DermaSpectrometer |
Countries
Taiwan
Outcome results
None listed