Atrial Fibrillation
Conditions
Keywords
Electrical Cardioversion
Brief summary
In patients with persistent atrial fibrillation (AF), electrical cardioversion is very effective in restoring sinus rhythm if modern, biphasic cardioverters are used. However, approximately 50 per cent of the successfully cardioverted patients experience a recurrence of AF within a few weeks. Therefore, valid predictors for AF recurrence would be of great clinical relevance, to avoid unnecessary procedures. In the PRE-ELECTRIC study, we will investigate the predictive value of potential new biomarkers with respect to AF recurrence within 30 days after electrical cardioversion. We will investigate serum and plasma biomarkers, electrocardiological markers and echocardiographic variables in this respect. The study will be undertaken as a prospective cohort study at Bærum Hospital, Vestre Viken Hospital Trust, with national and international collaborators.
Interventions
None listed
Sponsors
Oslo University Hospital
Lund University
Vestre Viken Hospital Trust
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients \> 18 years referred for electrical cardioversion for persistent atrial fibrillation * Signed, informed consent
Exclusion criteria
* Patients \< 18 years * Patients with paroxysmal atrial fibrillation * Patients unwilling to participate or without consent competence
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Atrial fibrillation recurrence | 30 days after electrical cardioversion | ECG-documented atrial fibrillation recurrence after successful cardioversion |
Countries
Norway
Contacts
Primary ContactArnljot Tveit, MD, PhD
Backup ContactMona Olufsen, RN
Outcome results
None listed