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Considerations on the Transfusion Threshold in Cardiac Surgery

Considerations on the Transfusion Threshold in Cardiac Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03346512
Enrollment
852
Registered
2017-11-17
Start date
2016-02-29
Completion date
2016-06-14
Last updated
2019-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgery

Brief summary

This is a retrospective observational study of the transfusion threshold in cardiac surgery. There is controversy in the literature regarding the transfusion threshold to be adopted, especially in a patient who has undergone cardiac surgery. Some authors suggest that the transfusion should be done in a restrictive way when a certain threshold in hemoglobin is reached, in order to avoid the risks it implies, especially infectious.This threshold is very controversial and remains to be defined (variations in the literature from 7g / dL to 9g / dL). Other authors conclude that there is no superiority of a restrictive transfusion compared to a more liberal transfusion, with regard to the morbidity or medical costs. It is therefore interesting to study, in a retrospective manner, the global and multidisciplinary management of patients who have undergone a cardiac surgery within the CHU Brugmann hospital, to analyze if they have been adequately transfused.

Interventions

PROCEDURECardiac surgery

Cardiac surgery

Sponsors

Pierre Wauthy
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\- Patients having undergone cardiac surgery (other than the placement of a pacemaker or defibrillator) within the CHU Brugmann hospital between 2006 and 2015

Exclusion criteria

* N/A

Design outcomes

Primary

MeasureTime frameDescription
Hemoglobin rateBaseline (just before cardiac surgery)Hemoglobin rate
Hematocrit rateBaseline (just before cardiac surgery)Hematocrit rate
International Normalized Ratio (INR)Baseline (just before cardiac surgery)Coagulation indicator
Creatinin rateBaseline (just before cardiac surgery)Renal function indicator
Total amount of blood perfusionsFive days after surgery (J5)Total amount of blood perfusions
Liquid balanceOne day after surgeryRatio between total fluid intake (perfusion) and loss (blood and urine)

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026