Spondyloarthritis
Conditions
Brief summary
The investigators hypothesize that the T1 Dixon post-Gadolinium and T2 Dixon sequences will show good diagnostic performances for active sacroiliitis compared to the reference test (Short tau inversion recovery) and clinical-biological criteria, which will allow a better diagnosis of active sacroiliitis
Interventions
DIAGNOSTIC_TESTImaging
Coronal oblique T1, Coronal oblique and axial STIR, Coronal oblique T1 Dixon, Coronal oblique and Axial T2 Dixon and T1 Dixon post Gadolinium
Sponsors
Centre Hospitalier Universitaire de Nīmes
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The patient must have given their free and informed consent and signed the consent form * The patient must be a member or beneficiary of a health insurance plan * The patient is at least 18 years old * The patient has a clinically diagnosed axial spondyloarthritis (axSpA) (ASAS or AMOR classification) * Patient has an active axSpA (BASDAI\>4)
Exclusion criteria
* The subject is participating in another study, or is in a period of exclusion determined by a previous study * The subject refuses to sign the consent * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship * The patient is pregnant or breastfeeding * The patient has a contra-indication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic performance of T1 Dixon post-Gadolinium and T2 Dixon for active sacroiliitis, according to subchondral edema status | Time 0 | compared to ASAS criteria incorporating Short tau inversion recovery and clinic-biological elements |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Diagnosis of enthesitis from T1 Gadolinium Dixon sequence vs ASAS criteria | Time 0 | Yes/no |
| Diagnosis of synovitis from T2 Dixon and T1 Gadolinium Dixon sequences vs ASAS criteria | Time 0 | Yes/no |
| Diagnosis of chronic sacroiliite (erosion or chondral scler osis, or fatty spinal replacement) by T1 Dixon pre-Gadolinium | Time 0 | Yes/No |
| Diagnosis of chronic sacroiliite (erosion or chondral sclerosis, or fatty spinal replacement) by conventional sequences | Time 0 | Yes/no |
Countries
France
Outcome results
None listed