Children, Only, Intracranial Pressure Increase, Intraocular Pressure, Trauma, Brain
Conditions
Brief summary
Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend). Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values.
Detailed description
Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend). Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values. Material and methods. Correlation and diagnostic test design study. Inclusion criteria: children with TBIs admitted to the emergency room and indication of catheter for ICP measurement. Exclusion criteria: injury or ophthalmic disease, glaucoma, encephalic death. Intraocular pressure was measured with electronic tonometer in both eyes prior to placement of the catheter for ICP measurement. Correlation was estimated with Spearman's Rho. The utility values of the diagnostic test were obtained from an Receiver Operating Characteristic curve.
Interventions
DIAGNOSTIC_TESTwith intraocular pressure high
Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.
DIAGNOSTIC_TESTwithout intraocular pressure high
Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.
Sponsors
Hospital Civil de Guadalajara
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to 15 Years
Healthy volunteers
No
Inclusion criteria
1. Children with severe trauma brain injury (Coma Glasgow Scale smaller than 9 points), 2. who have been admitted to the pediatric emergency room 3. and in whom the treating neurosurgeon has decided to place a catheter for intracranial pressure measurement.
Exclusion criteria
1. Ocular trauma, 2. brain death, 3. know eye disease, 4. refusal of parents or guardians to participate in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraocular pressure smaller than 20 mmHg | Immediately | Abscence of increased intraocular pressure (smaller than 20 mmHg) without intracranial pressure smaller than 20 mmHg. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intraocular pressure equal or more than 20 mmHg | Immediately | Intraocular pressure equal or more than 20 mmHg with Intracranial pressure equal or more than 20 mmHg |
Countries
Mexico
Contacts
Primary ContactKarla Isis I Aviles-Martinez, PhD
Backup ContactAdriana López-Enríquez, MD
Outcome results
None listed