Study of the Reversibility of Vigilance Dysfunction at 6 Months of Continuous Positive Airways Pressure (CPAP) in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)

Study of the Reversibility of Vigilance Dysfunction at 6 Months of Continuous Positive Airways Pressure (CPAP) in Patients With Obstructive Sleep

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03344263

Acronym

VISA

Enrollment

Registered

2017-11-17

Start date

2017-11-17

Completion date

2021-02-09

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vigilance Dysfunction

Brief summary

It is a monocentric prospective pilot study in Poitiers University Hospital, specifically analyzing the vigilance disorders in the Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and their reversibility after 6 months of Continuous positive airways pressure (CPAP). All subjects were administered a test of vigilance (Test of Attentional Performance) both before and after the 6 months of CPAP. The main objective is the study of the reversibility of alertness disorders on the number of omissions in the subtest visual vigilance of the TAP ( (Test of Attentional Performance) at 6 months of CPAP in the OSAHS in patients with a memory complaint.

Interventions

DIAGNOSTIC_TESTtests of attentional performance

tests of attentional performance before and after 6 months of continuous positive airways pressure

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 69 Years

Healthy volunteers

Inclusion criteria

* Patients aged 20-70 years * Memory disorders without memory problems in episodic memory * Presence of polysomnography of a obstructive sleep apnea/hypopnea syndrome (OSAHS) requiring Continuous positive airways pressure * Moderate OSAHS (Apnea Hypopnea Index ≥ 15 / hour with arousals ≥ 10) * Severe OSAHS (Apnea Hypopnea Index ≥ 30 / h)

Exclusion criteria

* Age \<20 years or ≥ 70 years * Neurodegenerative disease (Alzheimer's disease, Parkinson's disease) * Dysthyroidism * Severe depression, schizophrenia, bipolar disorder * Treatment with an effect on cognition: hypnotics, sedative * Chronic Obstructive Pulmonary Disease * Chronic alcoholism, other addictions * Contraindications to Magnetic Resonance Imaging * Refusal of equipment

Design outcomes

Primary

Measure	Time frame	Description
Study of the reversibility of vigilance disorders on the number of omissions in the subtest visual vigilance of the TAP	After 6 months of continuous positive airways pressure in the OSAHS patient	Reversibility of vigilance disorders on the number of omissions in the subtest visual vigilance of the TAP

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026