Anesthesia, Epidural, Labor Pain, Opioid
Conditions
Brief summary
Epidural anesthesia is used to relieve labour pain which helps reduce labour stress, increase comfort and improve cooperation with medical personnel. Administering opioid into the epidural space before cervical dilation of 4cm in the primigravida or 3cm in the multiparous can effectively reduce the pain levels with no effect on the labour progress. The aim of the study is to compare different opioids administered in this early labour stage.
Interventions
DRUGFentanyl
100mcg Fentanyl
DRUGSufentanil
10mcg sufentanil
Sponsors
Medical University of Warsaw
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
Participant not aware of opioid administered
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* parturient in labour without cervical dilation and regular uterine contractions
Exclusion criteria
* no consent * known allergy to administered opioid * contraindications to epidural analgesia * coagulopathies including platelet count of less than 100,000 * spine surgery in past
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain intensity according to Numerical Rating Scale (NRS) | up to 24 hours | till 4cm cervical dilation in primigravida or 3cm multiparous |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fetal heart rate | up to 24 hours | till 4cm cervical dilation in primigravida or 3cm multiparous |
| Blood pressure parturient | up to 24 hours | till 4cm cervical dilation in primigravida or 3cm multiparous |
| Heart rate of parturient | up to 24 hours | till 4cm cervical dilation in primigravida or 3cm multiparous |
Countries
Poland
Contacts
Primary ContactJan Bilawicz, MD
Outcome results
None listed