Epidemiology of Resistant Microbial Strains Among Different Groups of People (Healthy, Infected and Exposed to Animals)

Transfer Routes of Antibiotic Resistance

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03343119

Acronym

ABRESIST

Enrollment

708

Registered

2017-11-17

Start date

2012-03-27

Completion date

2019-08-31

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carbapenem Resistant P.Aeruginosa, ESBL Producing E.Coli, ESBL Producing K.Pneumoniae, Methicillin Resistant Staphylococcus Aureus (MRSA), Multidrug Resistant P.Aeruginosa, Vancomycin (Glycopeptide) Resistant Enterococcus (VRE)

Brief summary

This study investigates carriage rate and risk factors for acquiring multiresistant bacteria (ESBL producing E.coli and K.pneumoniae, carbapenem-resistant and multidrug resistant P.aeruginosa, MRSA and VRE) in hospitalised patients and healthy volunteers.

Interventions

None listed

Study design

Observational model

ECOLOGIC_OR_COMMUNITY

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

I group Hospitalised patients Inclusion Criteria * MDR bacteria (listed above) isolated from clinical specimen * hospitalisation to the Tartu University Hospital or North Estonia Medical Centre or West Tallinn Central Hospital or East-Tallinn Central Hospital or The Hospital of Reconstructive Surgery II group Healthy volunteers Inclusion Criteria * age \>6 months * have not received any antibacterial treatment in previous 3 months * have not been hospitalised in previous 3 months III group Dog owners Inclusion Criteria * age \>6 months * have not received any antibacterial treatment in previous 3 months * have not been hospitalised in previous 3 months * owning a dog IV group veterinarians Inclusion Criteria * have not received any antibacterial treatment in previous 3 months * have not been hospitaliZed in previous 3 months * working as a veterinarian V group pig farmers Inclusion Criteria * have not received any antibacterial treatment in previous 3 months * have not been hospitalized in previous 3 months * occupation as a pig farmer

Design outcomes

Primary

Measure	Time frame	Description
Colonization rate with multiresistant (MDR) bacteria in hospitalized patients	March 2012 - March 2014	To evaluate the impact of hospitalization for carriage and infection rate with MDR bacteria
Colonization rate with multiresistant (MDR) bacteria in healthy humans	March 2012 - March 2014	To evaluate the impact of animal exposure for carriage rate with MDR bacteria

Outcome results