PTSD
Conditions
Keywords
veterans, post traumatic stress disorder, depression
Brief summary
The purpose of Biomarker Establishment for Superior Treatment of PTSD is to accelerate research on the discovery of biological, neurological and neuroimaging markers for Post- Traumatic Stress Disorder (PTSD). The investigators hope to validate and extend the network efficiency and verbal memory biomarker for PTSD. The investigators hope to learn whether there are pretreatment biological factors that can predict response to therapy. They want to do this by understanding the brain network function, relating EEG to functional magnetic resonance imaging, and application of network analysis tool.
Interventions
OTHERPsychotherapy
Sponsors
New Mexico VA Healthcare System
Stanford University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of PTSD by VA clinicians and acceptance into PE or CPT treatment as part of the PCT * Veterans of any era
Exclusion criteria
* MRI safety contraindications * Active, uncontrolled medical illness * Acute suicidality * Current substance dependence * Current use of thyroid medication or active hyper/hypothyroidism * Neurological disorder affecting the CNS Seg stroke, epilepsy, tumorW or penetrating head injury * Use of PRN within 48 hours of the MRI/EEG
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Understanding the brain network function-neuroimaging and behavioral with Clinician-Administered PTSD Scale for DSM-5 | Approximately 3 months | We will be using CAPS 5 |
Countries
United States
Outcome results
None listed