Gait, Hemiplegic, Muscle Fatigue, Spasticity, Muscle, Stroke
Conditions
Brief summary
This study evaluates the effects of an isokinetic fatigue protocol of the quadriceps on the amount of co-contractions of this last with the hamstrings during a maximal isometric flexion movement in hemiparetic stroke patients. The effect of such a protocol on gait parameters and spasticity of the quadriceps will be evaluated also.
Interventions
PROCEDUREMuscle fatigue
Isokinetic quadriceps muscle fatigue of the paretic lower limb
Sponsors
University Hospital, Lille
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 80y * Hemiparesis after a first-ever stroke \> 3 months * Spasticity of the quadriceps muscle * Quadriceps strength at least at 3/5 (MRC testing) * Subject able to walk at least 2min without rest * Informed consent * Social security affiliation
Exclusion criteria
* Severe comprehension troubles (language, cognitive or psychiatric disorders) * History of previous stroke, locomotor or other neurological disorders * Locomotor troubles affecting the paretic arm * Contraindication to efforts : cardiac insufficiency, severe aortic valvular stenosis, recent heart failure, non treated high blood pressure, severe peripheral arterial disease * Pregnancy or breastfeeding * Adult subject to guardianship
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cocontraction Index (CCI) between the rectus femoris and the semitendinosus | one day | ratio of the RMS of a the rectus femoris when acting as antagonist to the effort intended (knee flexion) to the RMS of the same muscle when acting as an agonist during a reciprocal maximal isometric knee flexion effort (500 ms around the peak of rectified EMG |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Agonist Recruitment Index of the semitendinosus | one day | ratio of the RMS of a muscle acting as an agonist during a given period to its largest RMS value observed during the 500 ms around its agonist recruitment peak |
| Isometric peak knee flexion torque | one day | Isometric peak knee flexion torque assessed by a CONTREX dynamometer |
| Spasticity of the quadriceps | one day | Tardieu scale angle |
| spatio-temporal gait parameters at comfortable speed | one day | Gait speed |
| Cocontraction Index (CCI) between the other parts of the quadriceps and the semitendinosus muscle | one day | ratio of the RMS of a the vastus medialis, lateralis and intermedius when acting as antagonist to the effort intended (knee flexion) to the RMS of the same muscle when acting as an agonist during a reciprocal maximal isometric knee flexion effort (500 ms around the peak of rectified EMG |
| 10 metre walk test (10MWT) | one day | Assessment of max gait speed |
| 2 minute walk test (2MWT) | one day | Assessment of max walking endurance |
| perceived exertion at the end of the 2MWT (Borg Scale 6-20) | one day | — |
| Isometric peak knee extension torque | one day | Isometric peak knee extension torque assessed by a CONTREX dynamometer |
Countries
France
Outcome results
None listed