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Preoperative Vitamin D Levels and Respiratory Complications of General Anesthesia

Evaluation of the Effect of Preoperative Vitamin D Levels and Respiratory Complications of General Anesthesia

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03342651
Acronym
VitaminD
Enrollment
95
Registered
2017-11-17
Start date
2015-04-01
Completion date
2016-12-31
Last updated
2017-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D Deficiency

Keywords

Vitamin D, general anesthesia, respiratory complications

Brief summary

Vitamin D deficiency is a commonly observed health problem in the world. With a role in many chronic diseases and especially lung diseases, the importance of vitamin D deficiency in anesthesia management is increased. This research aims to investigate whether there is a correlation between the respiratory complications occurring in patients under general anesthesia and preoperative vitamin D levels.

Detailed description

This study included 95 adult cases aged from 18-65 years operated under general anesthesia. The cases had total 25-hydroxyvitamin D (25OHD) levels identified in blood samples before the operation. Patients given routine general anesthesia and postoperative monitoring procedures were assessed in terms of respiratory complications during anesthesia induction, extubation, anesthesia recovery and the first 24 hours postoperative. This research observed that patients with low preoperative 25OHD vitamin levels encountered respiratory complications related to general anesthesia more often. Especially in the early postoperative period there is a very significant difference between complications and low 25OHD vitamin levels. Our study results show that low vitamin D levels may be a potential risk in terms of respiratory complications related to general anesthesia causing severe morbidity and mortality increase. The results lead to the consideration that optimizing vitamin D levels in the preoperative period for patients undergoing general anesthesia may aid in reducing complications.

Interventions

OTHERVitamin D

Vitamin D, general anesthesia, respiratory complications

Sponsors

Ordu University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

\- American Society of Anesthesiologists I - II risk classification, healthy adult surgery cases

Exclusion criteria

* Thoracic surgery, those with severe respiratory, neuromuscular or endocrine system diseases, those with difficult intubation, morbid obesity, using vitamin D supplements and those who smoked

Design outcomes

Primary

MeasureTime frameDescription
Relationship between Vitamin D levels and respiratory complicationsPerioperative periodLow vitamin D levels may be a potential risk in terms of respiratory complications related to general anesthesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026