Perioperative Symptom Study of Lung Cancer (CN-PRO-Lung 1)

Conditions

Patient-reported Outcomes

Keywords

utility parameter, patient-reported outcome, perioperative symptom management, lung cancer

Brief summary

Investigators propose a multicenter prospective observational cohort study to develop and validate essential technical parameters for establishing the patient-reported outcome-based perioperative symptom management cohort in patients with lung cancer. With at least 300 patients with initial diagnosis of lung cancer and scheduled for surgery, this study will administer symptom assessments (MDASI-LC) and quality of life assessments (SIQOL) before surgery (typically within 3 days before surgery), daily after surgery (in hospital ≤ 14 days), and weekly after discharge, up to 4 weeks (±3 days) or the start day of postoperative oncologic treatment. In the upgraded research protocol, symptom and quality of life assessments (every 3 month for 1 year, every 6 month for 2-3 year, every 12 month for 4-5 year), as well as the follow-up of clinical outcomes will continue until 5 years after surgery.

Jia Liao, Xiaoqun Hu, Xing Wei, Wei Dai, Hongfan Yu et al. (13 authors)

BMC Cancer2025-04-29

10.1186/s12885-025-14191-z

Long‐Term Function Recovery Following Upper Versus Lower Lobectomy for Lung Cancer: A Multicenter Longitudinal Cohort Study

Xing Wei, Hongfan Yu, Bellinda L. King‐Kallimanis, Yangjun Liu, Lin Huang et al. (10 authors)

Thoracic Cancer2024-12-135 citations

10.1111/1759-7714.15505

Developing and validating utility parameters to establish patient-reported outcome-based perioperative symptom management in patients with lung cancer: a multicentre, prospective, observational cohort study protocol

Wei Dai, Shao‐Hua Xie, Rui Zhang, Xing Wei, Chuanmei Wu et al. (16 authors)

BMJ Open2019-10-0122 citations

10.1136/bmjopen-2019-030726

Using patient-reported outcomes to manage postoperative symptoms in patients with lung cancer: protocol for a multicentre, randomised controlled trial

Wei Dai, Yuanqiang Zhang, Wenhong Feng, Xiaoqing Liao, Yunfei Mu et al. (11 authors)

BMJ Open2019-08-0120 citations

10.1136/bmjopen-2019-030041

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

1. Be pathologically or clinically diagnosed as primary lung cancer before surgery; 2. Plan to undergo a surgical procedure.

Exclusion criteria

1. Aged younger than 18; 2. Diagnosis of cognitive impairment or unable to understand the study requirements.

Design outcomes

Primary

Measure	Time frame	Description
Perioperative symptom burden (severity, freqency and impact on daily functioning) measured by MDASI-LC	less than 6 weeks	We will use MD Anderson Symptom Inventory lung cancer module (MDASI-LC) to longitudinally assess the perioperative symptom burden for lung cancer patients. The symptom burden will be profiled as symptom severity, frequency of moderate to severe symptom and its interference with daily functioning.

Countries

China

Outcome results