Sepsis
Conditions
Brief summary
To observe the changes of plasma hepatocyte growth factor and soluble receptor s-Met levels in patients with sepsis, and to explore its clinical significance.
Detailed description
90 patients who diagnosed as sepsis were included in this study. Then keep blood samples from these patients in the first day, the third day, detect the hepatocyte growth factor and soluble receptor s-Met level in plasma byenzyme-linked immuno sorbent assay. Record Severity of illness and survival status of every patient within 28 days. Objective to evaluate the correlation between the level of hepatocyte growth factor and soluble receptor s-Met in plasma and the prognosis of the patients.
Interventions
taking peripheral blood of no more than 3ml
Sponsors
Jingyuan,Xu
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. Patients admitted to ICU diagnosed of sepsis(sepsis3.0 criteria) 2. Patients signing informed consent
Exclusion criteria
1. Age is less than 18 years old or more than 80 years old 2. Pregnant women 3. Patients with tumor、hepatitis、liver cirrhosis、acute myocardial infarction、chronic renal tubular nephritis、interstitial pneumonia、acute pancreatitis、systemic lupus erythenatosus、ulcerative colitis、crohn's disease、HELLP syndrome 4. Prothrombin time is extension in patients with after liver transplantation 5. Patients with chronic renal failure 6. Patients after kidney transplantation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| mortality | 28-day | 28-day mortality |
Countries
China
Contacts
Primary Contactchenglong liang, master
Backup Contactyi yang, doctor
Outcome results
None listed