Trauma
Conditions
Brief summary
Prospective randomized clinical trial Compare the goal-directed fluid therapy using esophageal Doppler and classic fluid therapy
Detailed description
Goal directed fluid therapy becomes issue for enhanced recovery after surgery. In goal directed therapy, dynamic parameters, like stroke volume and cardiac output, is important. Esophageal Doppler is one of device which provides dymanic parameters. In severe trauma cases, the effect of goal directed therapy is not known yet. So the aim of this study is comparing the results of goal directed therapy using esophageal Doppler and conventional fluid therapy.
Interventions
DEVICEesophageal Doppler
Goal directed fluid therapy using dynamic parameters from esophageal Doppler
Sponsors
Ajou University School of Medicine
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Severe trauma patients who undergo general anesthesia * Initial serum lactate level \> 2mmol/L
Exclusion criteria
* Severe traumatic brain injury * THoracic surgery * Age \< 19 years old * Impending arrest or post CPR state * Severe facial trauma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lactate | Immediate postoperative (=initial ICU admission) | Unit is mmol/L Inclusion criteria is initial lactate \> 2mmol/L. Whole hospital use same device and unit to measure lactate. In this study, POCT lactate won't be used. After surgical resuscitation, lactate level is independent predictor of survival, because it represents tissue oxygenation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Acute Physiology and Chronic Health Evaluation II (APACHE II) score | Immediate postoperative | ICU patient scoring system, score from 0 to 71, higher scores correspond to more severe disease and a higher risk of death |
| Creatinine | Immediate postop | Kidney function |
Countries
South Korea
Outcome results
None listed