Platelet Function With Various Storage Techniques

The Impact of Various Storage Techniques on Platelet Function

Status

Withdrawn

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03338660

Enrollment

Registered

2017-11-09

Start date

2018-07-15

Completion date

2020-07-15

Last updated

2019-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Platelet Dysfunction Due to Drugs

Brief summary

Platelet function will be tested in individuals on antiplatelet medications to determine the optimal storage methodology.

Detailed description

Subjects will undergo administration of antiplatelet drugs and then will receive platelets stored in a variety of methods. Platelet function will be measured serially.

Interventions

BIOLOGICALInfusion of Platelets

Platelets will be stored using novel, FDA approved, technique. Subjects will receive infusion of platelets stored by novel technique, routine storage, and placebo (saline).

BIOLOGICALPlacebo

Subjects will receive infusion placebo (saline).

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE (Investigator, Outcomes Assessor)

Masking description

the assesor of platelet function and the PI will be blinded to group.

Intervention model description

crossover study of various storage infusions techniques with each subject receiving various fluids aliquots.

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Normal subjects

Exclusion criteria

* Pre existing antiplatelet drugs

Design outcomes

Primary

Measure	Time frame	Description
Change in platelet function	1 hour post-transfusion	Frozen platelets will result in improvement in platelet function after transfusion.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026