Urinary Disorders in Patients With Multiple Sclerosis: Invasive Vs Non-invasive Investigations.

Prospective Randomized Controlled Trial Comparing the Non-invasive vs the Invasive Investigations in Multiple Sclerosis Patients With Urinary Disorders.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03336424

Enrollment

Registered

2017-11-08

Start date

2017-10-01

Completion date

2019-10-31

Last updated

2018-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis, Urinary Bladder, Neurogenic, Urodynamics

Keywords

MS, Multiple sclerosis, urinary Bladder, Neurogenic, Urodynamics, Randomized controlled trial

Brief summary

The objective of the study is to describe the current status of MS patients with urinary disorders in Lebanon, and to demonstrate whether invasive investigations improve the management of these patients compared to an optimal non-invasive approach.

Detailed description

All patients will be evaluated by an urologist, then randomized into 2 groups, the first group will benefit from non-invasive investigations and will be treated accordingly, the second group will benefit from an urodynamic assessment and will also be treated accordingly. An evaluation will be made one month, 3 months and 6 months after the first visit.

Interventions

DIAGNOSTIC_TESTNon-invasive investigations

Ultrasound, blood tests, urine analysis and culture, uroflowmetry

DIAGNOSTIC_TESTInvasive investigations

Cystomanometry, pressure flow study, EMG

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Intervention model description

Parallel study, where group A receives non-invasive investigations and group B receives Invasive investigations.

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* MS with urinary symptoms

Exclusion criteria

* BPH LUTS * Bladder cancer * prostate cancer * urethral stenosis

Design outcomes

Primary

Measure	Time frame	Description
urinary symptoms	6 months	filling and voiding urinary symptoms (UBQMS: Urinary Bothersome Questionnaire in Multiple Sclerosis), Voising Score Ranges from 0 to 3 ( 3 being most severe bother), Filling score ranges from 0 to 3 ( 3 being most severe bother).
urinary quality of life	6 months	SF-QUALIVEEN: Short Form - health related quality of life questionnaire for urinary disorders in patients with neurological conditions. score ranges from 0 to 4 ( 4 being the worst quality of life).

Countries

Lebanon

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026