Adult, Anthropometry, Cohort Studies, Diet, Food, and Nutrition, Diseases Category, Exercise, Humans, Internet, Mortality, Surveys and Questionnaires
Conditions
Keywords
determinants of dietary patterns and nutritional status, Food additives, Food processing, Exclusion diets, vegetarian diet, vegan diet, Organic food, pesticide exposure, sustainability, Gut microbiota, Food labeling, Dietary supplements, Food based dietary guidelines, Psychological determinants of food behavior, Geographical determinants of food behavior, Breastfeeding, Mental health, Cancer, Cardiovascular and cardiometabolic health, Multimorbidity
Brief summary
The NutriNet-Santé study was set up to investigate nutrition and health relationships. Specifically, it was the first web-based cohort worldwide on such a large scale (n=171 000 as of 2021) focused on the complex link between nutrition and health status. It is characterized by a very detailed assessment of nutritional exposure and dietary behavior. https://etude-nutrinet-sante.fr/ https://info.etude-nutrinet-sante.fr/en
Detailed description
NutriNet-Santé is a large-scale (n=171,000) web-based cohort coordinated by EREN, launched in France in 2009 to investigate nutrition and health relationships. All required ethics authorisations have been obtained (listed here). NutriNet-Santé participants regularly fill questionnaires through a dedicated and secure website, providing extensive, high-quality nutritional and non-nutritional data, including repeated data on socio-demographics and lifestyle (yearly), anthropometrics (every 6 months), dietary intake (every 6 months), physical activity (IPAQ questionnaire, yearly)5 and health status (every 6 months). NutriNet-Santé is characterised by a very detailed and up-to-date assessment of nutritional exposure and dietary behaviours. Usual dietary intakes are assessed at baseline and every 6 months thereafter through a series of 3 non-consecutive randomly assigned 24h dietary records. Daily energy, alcohol, micro- and macronutrient intakes are calculated using the published NutriNet-Santé food composition database (\>3,500 generic items). All major health events (e.g., cancers, cardio- and cerebrovascular diseases) are reported by the participants and validated by an expert committee of physicians based on medical records, and/or retrieved from the French National Health Insurance medico-administrative databases to limit potential reporting bias. In turn, mortality data are obtained from the exhaustive French National Mortality Registry (CépiDC). The number of incident events already registered is as follows: 4,200 cancers and 1,240 deaths. A sub-sample of the cohort (n=20,000) provided blood and urine samples, currently stored at -80°C in EREN's biobank.
Interventions
None listed
Sponsors
Institut National de la Santé Et de la Recherche Médicale, France
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Conservatoire national des Arts et Métiers
University of Paris 13
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* aged over 15 years * access to internet
Exclusion criteria
* aged under 15 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cancers using health questionnaire and/or the website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| CVD using health questionnaire and/or the dedicated website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| type 2 diabetes using health questionnaire and/or the website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| hypertension using health questionnaire and/or the website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| metabolic syndrome using health questionnaire and/or the website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| depression using health questionnaire and/or the website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| migraine using health questionnaire and/or the website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| rheumatoid arthritis using health questionnaire and/or the website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| cognitive decline using health questionnaire and/or the website for declaration of major health events | every 6 months after registration, up to 10 years of follow-up | self reported |
| quality of life using the SF-36 questionnaire | every 6 months after registration, up to 10 years of follow-up | self reported |
| Weight using anthropometric questionnaire | every year after registration, up to 10 years of follow-up | self reported |
| Height using anthropometric questionnaire | every year after registration, up to 10 years of follow-up | self reported |
| Mortality | continuously updated | CepiDC exhaustive national registry |
| Mental health (incl. anxious disorders, sleep disorders, addictive behaviors, eating disorders) | repeatedly during followup | self reported though validated scales and/or questionnaires |
| SARSCOV-2 (Covid 19) infection | regular update for a subsampe of the cohort from 2020 | serology + questionnaires on symptoms |
| multi-morbidity (mental and physical health) | continuous update | combination of previsously listed mental and physical health outcomes |
Countries
France
Contacts
Primary ContactMathilde Touvier, Dr
Outcome results
None listed