Human Immunodeficiency Virus
Conditions
Brief summary
The aim of this study is to assess the feasibility and the effects of a 6-week telerehabilitation on the three domains of the International Classification of Functioning, Disability and Health in HIV-infected patients under highly active antiretroviral therapy (HAART). HIV-infected patients were randomized either into an Endurance and Resistance Training Exercise (ERTE) group or a control (CON) group. Telerehabilitation was realized in a public fitness center, with online guidance and weekly telephone advice, 3 times per week for 6 weeks. Feasibility was determined by recruitment rate, retention rate and adverse events. Secondary outcomes were impact on body composition, inflammation and coagulation (C-reactive protein, D-dimer), physical fitness and quality of life (WHOQOL-HIV).
Interventions
BEHAVIORALEndurance ad Resistance Training Exercise
Patients received a 6-week tele-supervised rehabilitation with 3 exercise sessions per week
Sponsors
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 18 years or older * under HAART treatment * native French speaker
Exclusion criteria
* AIDS diagnosis * physical and/or psychiatric impairments that seriously impaired physical activity * pregnant * Unstable (defined by any modification of health outcomes during the last 6 months).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recruitment rate | At study completion (after 6 weeks) | Number of eligible participants who enrolled in the program out of the number were recruited |
| Retention rate | At study completion (after 6 weeks) | Percentage of patients lost to follow-up |
| Adverse events | At study completion (after 6 weeks) | Percentage of patients who experienced one or more adverse events |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| C-reactive protein | Assessments at baseline and at 12 weeks | C-reactive protein is measured by a blood test |
| D-dimer | Assessments at baseline and at 12 weeks | D-dimer is measured by a blood test |
| CD4+ T cell counts | Assessments at baseline and at 12 weeks | CD4+ T cell counts is measured by a blood test |
| Viral load | Assessments at baseline and at 12 weeks | Viral load is measured by a blood test |
| Weight | Assessments at baseline and at 6 weeks | Weight (kg) is measured by using a bioelectrical impedance analysis |
| Flexibility | Assessments at baseline and at 6 weeks | Flexibility is measured by Toe touch test and sit and reach test |
| Lower body muscular strength | Assessments at baseline and at 6 weeks | Lower body muscular strength is measured by 30-s chair-stand test |
| Upper limb strength | Assessments at baseline and at 6 weeks | Upper limb strength is measured by hand grip strength tool |
| Quality of life | Assessments at baseline and at 6 weeks | Quality of life is measured by World Health Organization Quality of Life HIV Instrument |
| Functional exercise capacity | Assessments at baseline and at 6 weeks | Functional exercise capacity is measured by a 6-minute walk test |
| Lean body mass | Assessments at baseline and at 6 weeks | Lean body mass (kg) is measured by using a bioelectrical impedance analysis |
| Fat body mass | Assessments at baseline and at 6 weeks | Lean body mass (kg) is measured by using a bioelectrical impedance analysis |
Outcome results
None listed